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一项关于输尿管支架置入联合初次手术失败后二期输尿管镜检查的前瞻性试验。

A prospective trial on ureteral stenting combined with secondary ureteroscopy after an initial failed procedure.

作者信息

Ji Changwei, Gan Weidong, Guo Hongqian, Lian Huibo, Zhang Shiwei, Yang Rong, Zhao Xiaozhi

机构信息

Department of Urology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.

出版信息

Urol Res. 2012 Oct;40(5):593-8. doi: 10.1007/s00240-012-0476-0. Epub 2012 Apr 12.

Abstract

The aim of this study is to investigate the impact of the intentional ureteral stenting on the success rate of calculus extraction by second ureteroscopy, when the initial ureteroscopy failed. We prospectively enrolled 512 patients with ureteral calculi who underwent ureteroscopies from April 2005 to May 2011. The patients with failed initial ureteroscopies were classified into two groups depending on the stent type: the Double-J stent and the ureteral catheter group. The secondary ureteroscopies were performed in a short period (3-22 days). Data were abstracted on stone size, location, patient demographics, outcome and complications. A total of 453 patients had success after the initial ureteroscopy and the success rate was 88.5%. Of the 59 failed patients, 40 were managed by reureteroscopy with Double-J stent placement and 19 with ureteral catheters. There were no statistically significant differences between patients in Double-J stent and ureteral catheter group in the aspects of age, primary stone size, gender, stone location and stone-free rate [39/40 (97.5%) versus 19/19 (100%), p > 0.05]. Moreover, the mean stents retaining period before the second ureteroscopy was significantly shorter in the ureteral catheter group, when compared with the Double-J stent group (3.9 versus 16.9 days, p < 0.01). The complications were moderate and not significantly different between the two groups (p > 0.05). Indwelling a ureteral stent leads to a high subsequent success rate for second ureteroscopy following an initial failed procedure. In addition to Double-J stent, the ureteral catheter stent was an effective alternative with shorter retaining period, especially for impacted stones.

摘要

本研究旨在探讨在初次输尿管镜检查失败时,有意放置输尿管支架对二次输尿管镜取石成功率的影响。我们前瞻性纳入了2005年4月至2011年5月期间接受输尿管镜检查的512例输尿管结石患者。初次输尿管镜检查失败的患者根据支架类型分为两组:双J支架组和输尿管导管组。二次输尿管镜检查在短时间内(3 - 22天)进行。收集了结石大小、位置、患者人口统计学资料、结果及并发症等数据。共有453例患者初次输尿管镜检查成功,成功率为88.5%。在59例失败患者中,40例通过再次输尿管镜检查并放置双J支架进行处理,19例放置输尿管导管。双J支架组和输尿管导管组患者在年龄、原发结石大小、性别、结石位置及结石清除率方面无统计学显著差异[39/40(97.5%)对19/19(100%),p>0.05]。此外,与双J支架组相比,输尿管导管组二次输尿管镜检查前支架留置的平均时间明显更短(3.9天对16.9天,p<0.01)。两组并发症程度中等,且无显著差异(p>0.05)。留置输尿管支架可使初次手术失败后的二次输尿管镜检查获得较高的成功率。除双J支架外,输尿管导管支架是一种有效的替代方法,留置时间更短,尤其适用于嵌顿性结石。

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