PaGeFinder：时空模式基因的定量识别。
PaGeFinder: quantitative identification of spatiotemporal pattern genes.
机构信息
Department of Chemical Biology, College of Chemistry and Chemical Engineering, The Key Laboratory for Chemical Biology of Fujian Province, School of Life Sciences, Xiamen University, Xiamen, Fujian, P R China.
出版信息
Bioinformatics. 2012 Jun 1;28(11):1544-5. doi: 10.1093/bioinformatics/bts169. Epub 2012 Apr 6.
Abstract
UNLABELLED
Pattern Gene Finder (PaGeFinder) is a web-based server for on-line detection of gene expression patterns from serial transcriptomic data generated by high-throughput technologies like microarray or next-generation sequencing. Three particular parameters, the specificity measure, the dispersion measure and the contribution measure, were introduced and implemented in PaGeFinder to help quantitative and interactive identification of pattern genes like housekeeping genes, specific (selective) genes and repressed genes. Besides the on-line computation service, the PaGeFinder also provides downloadable Java programs for local detection of gene expression patterns.
AVAILABILITY
摘要
未标记
模式基因发现器（PaGeFinder）是一个基于网络的服务器，用于在线检测高通量技术（如微阵列或下一代测序）生成的串行转录组数据中的基因表达模式。PaGeFinder 中引入并实现了三个特定参数，即特异性度量、离散度度量和贡献度量，以帮助定量和交互式识别模式基因，如管家基因、特定（选择性）基因和受抑制基因。除了在线计算服务外，PaGeFinder 还提供可下载的 Java 程序，用于本地检测基因表达模式。
可用性
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