Sýkora J, Stozický F
Dĕtská klinika fakultní nemocnice, Plzen.
Cesk Pediatr. 1990 Apr;45(4):193-6.
The authors submit their experience with the examination of immunoglobulins and albumin in the faeces of patients with different diseases of the gastrointestinal tract. The presence of antibodies IgA, sIgA, IgM and albumin were assessed in lavages from the rectum or supernatant of the faeces, using the qualitative method of double immunodifussion according to Ouchterlony. A normal finding is characterized by the presence of IgA, sIgA. For evaluation of the clinical importance and applicability of the examination method the authors draw attention to the importance of asessing the degree of positive or negative correlation between findings and the final diagnosis. The authors present three basic pictures; acute inflammation, chronic inflammation, non-inflammatory exsudation (exsudative enteropathy). They analyze the clinical application of different findings and their practical impact. They give an account of limiting factors in the evaluation of the presence of immunoglobulins and albumin in faeces.
作者介绍了他们对不同胃肠道疾病患者粪便中免疫球蛋白和白蛋白检测的经验。采用奥克特洛尼双免疫扩散定性方法,评估直肠灌洗液或粪便上清液中抗体IgA、sIgA、IgM和白蛋白的存在情况。正常结果的特征是存在IgA、sIgA。为了评估检测方法的临床重要性和适用性,作者提请注意评估检测结果与最终诊断之间正相关或负相关程度的重要性。作者呈现了三种基本情况:急性炎症、慢性炎症、非炎性渗出(渗出性肠病)。他们分析了不同检测结果的临床应用及其实际影响。他们阐述了评估粪便中免疫球蛋白和白蛋白存在情况的限制因素。