Bactec Mycosis IC/F、BacT/Alert FA 和 BacT/Alert FN 血培养瓶在检测念珠菌血症方面的临床比较。
Clinical comparison of the Bactec Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN blood culture vials for the detection of candidemia.
机构信息
Division of Clinical Microbiology F 72, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden.
出版信息
Diagn Microbiol Infect Dis. 2012 Jun;73(2):153-6. doi: 10.1016/j.diagmicrobio.2012.02.020. Epub 2012 Apr 10.
The present study analyzed the performance of Bactec Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN vials in detection and time to detection (TTD) of Candida spp. in 179 simultaneous blood cultures. The Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN vials could detect Candida spp. in 144 (80.45%) of 179, 149 (83.24%) of 179, and 8 (4.47%) of 179 samples, respectively. With the presence of antifungal therapy, the numbers of positive vials were higher in BacT/Alert FA compared to Mycosis IC/F, 87/99 versus 73/99, respectively (P < 0.05). TTD (SD) for C. albicans was shorter in Mycosis IC/F than in BacT/Alert FA vials without antifungal therapy, 20.89 (9.33) versus 28.26 (9.77), respectively (P < 0.01). The detection of Candida spp., with concomitant bacteremia, was higher in Mycosis IC/F than in BacT/Alert FA vials, 28/30 and 19/30, respectively (P = 0.01). The present data show that the use of Bactec Mycosis IC/F together with BacT/Alert FA vials might improve the detection of Candida spp.
本研究分析了 Bactec 真菌培养瓶（Mycosis IC/F）、BacT/Alert FA 和 BacT/Alert FN 培养瓶在 179 份同时进行的血培养中检测和检测时间（TTD）对念珠菌属的性能。Mycosis IC/F、BacT/Alert FA 和 BacT/Alert FN 培养瓶分别可在 179 份样本中的 144 份（80.45%）、179 份样本中的 149 份（83.24%）和 179 份样本中的 8 份（4.47%）中检测到念珠菌属。在存在抗真菌治疗的情况下，BacT/Alert FA 培养瓶中的阳性瓶数高于 Mycosis IC/F 培养瓶，分别为 87/99 比 73/99（P<0.05）。在没有抗真菌治疗的情况下，Mycosis IC/F 培养瓶中 C. albicans 的 TTD（SD）比 BacT/Alert FA 培养瓶短，分别为 20.89（9.33）比 28.26（9.77）（P<0.01）。在合并菌血症的情况下，Mycosis IC/F 培养瓶中念珠菌属的检测率高于 BacT/Alert FA 培养瓶，分别为 28/30 和 19/30（P=0.01）。本研究数据表明，联合使用 Bactec 真菌培养瓶和 BacT/Alert FA 培养瓶可能会提高念珠菌属的检测率。
Zotero 插件