Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Int J Food Microbiol. 2012 May 15;156(2):147-51. doi: 10.1016/j.ijfoodmicro.2012.03.016. Epub 2012 Mar 23.
The spread of antibiotic resistance via meat poses a serious public health concerns. During 2007-2009, a total of 586 retail meat samples (318 pork and 268 chicken meats) were collected from three provinces (Bac Ninh, Ha Noi and Ha Tay) of North Vietnam to determine the prevalence of Salmonella. Isolates were characterized by serotyping and antibiotic susceptibility testing. Approximately 39.6% (n=126) of pork and 42.9% (n=115) of chicken samples were Salmonella-positive, and 14 Salmonella serovars were identified. Anatum (15.8%) was the most common serovar, followed by Infantis (13.3%), Emek (10.4%), Derby and Rissen (9.5%), Typhimurium (9.1%), Reading (7.5%) and London (6.2%). The isolation frequency of serovars Enteritidis, Albany, Hadar, Weltevreden, Newport and Blockey ranged from 1.2%-5.8%. Resistance to at least one antibiotic agent was detected in 78.4% of isolates (n=189) and the most frequent resistance were to tetracycline (58.5%), sulphonamides (58.1%), streptomycin (47.3%), ampicillin (39.8%), chloramphenicol (37.3%), trimethoprim (34.0%) and nalidixic acid (27.8%). No Salmonella isolates were resistant to ceftazidime. Chicken isolates had higher resistance to antibiotic agents than pork isolates (P<0.05). It showed that 159 Salmonella isolates belong to the 14 serovars were multidrug resistant (MDR) and 50 MDR patterns were found. This study indicated that Salmonella serovars isolated from retail meat samples were resistant to multiple antibiotics and this resistance was widespread among different serovars. The widespread resistance may have arisen from misuse or overuse of antibiotics during animal husbandry in North Vietnam.
食源性抗生素耐药性传播引发严重公共卫生关注。2007-2009 年，从越南北部的北宁省、河内市和海阳省三个省共采集了 586 份零售肉类样本（318 份猪肉和 268 份鸡肉），以确定沙门氏菌的流行情况。通过血清分型和抗生素药敏试验对分离株进行了特征描述。约 39.6%（n=126）的猪肉和 42.9%（n=115）的鸡肉样本呈沙门氏菌阳性，鉴定出 14 种沙门氏菌血清型。安藤（15.8%）是最常见的血清型，其次是婴儿（13.3%）、埃默克（10.4%）、德比和里森（9.5%）、伤寒（9.1%）、里丁（7.5%）和伦敦（6.2%）。肠炎、奥尔巴尼、哈达尔、韦尔特维登、纽波特和布洛克利血清型的分离频率为 1.2%-5.8%。78.4%（n=189）的分离株至少对一种抗生素耐药，最常见的耐药性是四环素（58.5%）、磺胺类药物（58.1%）、链霉素（47.3%）、氨苄西林（39.8%）、氯霉素（37.3%）、甲氧苄啶（34.0%）和萘啶酸（27.8%）。没有分离出对头孢他啶耐药的沙门氏菌。鸡肉分离株对抗生素的耐药性高于猪肉分离株（P<0.05）。结果表明，159 株沙门氏菌分离株属于 14 种血清型，均为多重耐药（MDR），共发现 50 种 MDR 模式。本研究表明，从零售肉类样本中分离出的沙门氏菌血清型对多种抗生素耐药，且不同血清型间耐药性广泛存在。这种广泛的耐药性可能是由于越南畜牧业中抗生素的不当或过度使用所致。
