Division of Obstetrics and Gynecology, Department of Perinatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
J Perinat Med. 2012 Jan 23;40(3):255-7. doi: 10.1515/jpm-2011-0233.
To test the hypothesis that the presence of a male affects birth weight of its female co-twin.
We evaluated a large population dataset of bichorionic twins after exclusion of potential confounders and after controlling for parity and gestational age. We tested the hypotheses that males (M) are heavier than females (F) irrespective of gender mix, parity and gestational age, and the hypothesis that birth weight of twins might be influenced by the gender of the co-twin.
There were 819 MM pairs, 777 FF pairs and 1097 MF sets, for a total of 2735 males and 2651 female twins. Male twins were heavier than female twins, irrespective of parity or gestational age; twins born to multiparas were heavier than twins born to nulliparas, except for very preterm births (≤32 weeks); males from MF pairs were heavier than males from MM pairs, but the mean birth weight of females from MF was not different from that of females from FF sets suggesting no "masculinization" effect of the male on birth weight of its female co-twin, irrespective of parity and gestational age.
After exclusion of potential confounders and controlling for chorionicity, parity, and gestational age, our data do not support the presence of a "masculinization" effect on birth weight.
验证男性的存在是否会影响其女性同卵双胞胎的出生体重的假设。
我们排除了潜在的混杂因素，并控制了多胎妊娠和胎龄后，评估了双绒毛膜双胞胎的大型人群数据集。我们检验了以下假设：男性（M）无论性别组合、多胎妊娠和胎龄如何，都比女性（F）重；以及双胞胎的出生体重可能受到同卵双胞胎性别影响的假设。
共有 819 对 MM 双胞胎、777 对 FF 双胞胎和 1097 对 MF 双胞胎，总计有 2735 名男性和 2651 名女性双胞胎。无论多胎妊娠或胎龄如何，男性双胞胎都比女性双胞胎重；除了极早产儿（≤32 周）外，多胎妊娠的双胞胎比单胎妊娠的双胞胎重；MF 对中的男性比 MM 对中的男性重，但 MF 对中的女性出生体重与 FF 对中的女性出生体重没有差异，这表明男性对其女性同卵双胞胎的出生体重没有“男性化”影响，无论多胎妊娠和胎龄如何。
在排除潜在混杂因素并控制了绒毛膜性、多胎妊娠和胎龄后，我们的数据不支持存在对出生体重的“男性化”影响。
