Melbourne Dental School, The University of Melbourne, Melbourne, Vic., Australia.
Caries Res. 2012;46(2):161-9. doi: 10.1159/000337099. Epub 2012 Apr 11.
BACKGROUND/AIMS: This study aimed to compare and contrast in vitro six methods to determine the most accurate method for detecting approximal carious lesions in primary molars.
Extracted primary molars (n = 140) were stored in 0.02% chlorhexidine solution and mounted in light-cured resin in pairs. The six carious lesion detection methods used by the three examiners to assess approximal carious lesions were visual inspection, digital radiography, two transillumination lights (SDI and NSK), and two laser fluorescence instruments (CDD and DDP). Five damaged teeth were discarded. The teeth (n = 135) were sectioned, serially ground, and examined under light microscopy using Downer's histological (HST) criteria as the gold standard. Intra- and inter-examiner reliability, agreement with HST, specificity, sensitivity, receiver operating characteristic (ROC) curves, and areas under the curve were calculated.
This study found visual inspection to be the most accurate method when validated by histology. Transillumination with NSK light had the highest specificity, and digital radiography had the highest sensitivity for detecting enamel and/or dentinal carious lesions. Combining specificity and sensitivity into the area under ROC curves, enamel plus dentinal lesions were detected most accurately by visual inspection followed by digital radiography; dentinal lesions were detected most accurately by digital radiography followed by visual inspection.
None of the four newly developed methods can be recommended as suitable replacements for visual inspection and digital radiography in detecting carious lesions on approximal surfaces of primary molars, and further developmental work is needed.
背景/目的:本研究旨在比较和对比六种体外方法,以确定检测乳磨牙近中龋损最准确的方法。
提取的乳磨牙(n=140)用 0.02%洗必泰溶液储存并成对固定在光固化树脂中。三位检查者使用六种龋损检测方法来评估近中龋损,包括肉眼观察、数字射线照相、两种透照灯(SDI 和 NSK)和两种激光荧光仪器(CDD 和 DDP)。五颗受损牙齿被剔除。将牙齿(n=135)切成薄片,连续研磨,并使用 Downer 的组织学(HST)标准在光学显微镜下检查,作为金标准。计算了内部和外部检查者的可靠性、与 HST 的一致性、特异性、敏感性、接收者操作特征(ROC)曲线和曲线下面积。
本研究发现,在通过组织学验证时,肉眼观察是最准确的方法。NSK 透照光的特异性最高,数字射线照相对检测釉质和/或牙本质龋损的敏感性最高。将特异性和敏感性结合到 ROC 曲线下的面积中,肉眼观察结合数字射线照相对检测釉质加牙本质病变最准确;数字射线照相结合肉眼观察对检测牙本质病变最准确。
在检测乳磨牙近中面龋损方面,没有一种新开发的方法可以替代肉眼观察和数字射线照相,需要进一步的开发工作。