Restall J, Johnston I G, Robinson D N
Cambridge Military Hospital, Aldershot, Hampshire.
Anaesthesia. 1990 Nov;45(11):938-40. doi: 10.1111/j.1365-2044.1990.tb14623.x.
A double-blind, parallel group study using flumazenil and placebo was carried out to determine whether patients who received flumazenil would awake more quickly and whether this drug would reverse the protection conferred by midazolam on the psychic sequelae of ketamine. Fifty female patients were studied. The results showed that there was a significant reduction in awakening time (p = 0.02) and a very significant increase (p = 0.001) in the incidence of dreams in the flumazenil group.
进行了一项使用氟马西尼和安慰剂的双盲平行组研究，以确定接受氟马西尼的患者是否会更快醒来，以及该药物是否会逆转咪达唑仑对氯胺酮精神后遗症的保护作用。研究了50名女性患者。结果显示，氟马西尼组的苏醒时间显著缩短（p = 0.02），梦境发生率显著增加（p = 0.001）。
