Ceriani R L, Taylor-Papadimitriou J, Peterson J A, Brown P
In Vitro. 1979 May;15(5):356-62. doi: 10.1007/BF02616142.
Two major types of cells can be cultured from early lactation human milks: a colony-forming epithelial cell and an adherent nondividing cell referred to as a foam cell. The epithelial cells show a positive reaction with a specific antiserum reactive against membrane components of the milk fat globule, whereas the foam cells do not. The nondividing foam cells are phagocytic and can be killed by silica particles; they produce lysozyme, are resistant to trypsinization, and have Fc receptors. These properties, together with the lack of reaction with antiserum to the milk fat globule membrane, suggest that the foam cells are not terminally differentiated epithelial cells, but tissue macrophages.
一种是集落形成上皮细胞，另一种是贴壁不分裂细胞，称为泡沫细胞。上皮细胞与一种针对乳脂肪球膜成分的特异性抗血清呈阳性反应，而泡沫细胞则无此反应。不分裂的泡沫细胞具有吞噬作用，可被二氧化硅颗粒杀死；它们能产生溶菌酶，对胰蛋白酶消化有抗性，且具有Fc受体。这些特性，再加上与乳脂肪球膜抗血清缺乏反应，表明泡沫细胞不是终末分化的上皮细胞，而是组织巨噬细胞。
