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诊断糖尿病患者的冠状动脉疾病。

Diagnosis of coronary artery disease in persons with diabetes mellitus.

机构信息

Division of Cardiology, Department of Medicine, University of California-Irvine, 333 City Boulevard West, Orange, CA 92868-3298, USA.

出版信息

Curr Diab Rep. 2012 Jun;12(3):286-93. doi: 10.1007/s11892-012-0273-8.

DOI:10.1007/s11892-012-0273-8
PMID:22528595
Abstract

Coronary heart disease (CHD) is the leading cause of morbidity and mortality in patients with diabetes. Asymptomatic CHD in these patients is elusive and carries a poor prognosis given the fact that an unheralded acute myocardial infarction or sudden cardiac death frequently constitutes its first presentation. Because effective screening for asymptomatic patients with type 2 diabetes for both the presence and severity of CHD is intuitively appealing, we have summarized the utility and prognostic value of various diagnostic modalities (both functionally and anatomically) in enhancing risk stratification and leading to improved and more aggressive management of the risk factors. There exist some evidence and recommendations for screening of asymptomatic persons with diabetes using certain modalities. More research is needed to define potential subsets of patients with diabetes who may benefit from additional testing for asymptomatic CHD.

摘要

冠心病(CHD)是糖尿病患者发病率和死亡率的主要原因。这些患者无症状性 CHD 难以捉摸,预后不良,因为其首发表现通常是突发急性心肌梗死或心源性猝死。由于对 2 型糖尿病患者进行无症状性 CHD 的存在和严重程度的有效筛查具有直观吸引力,因此我们总结了各种诊断方式(功能和解剖学)在增强风险分层和导致改善及更积极的危险因素管理方面的作用和预后价值。某些方式筛查无症状糖尿病患者有一定的证据和推荐。需要进一步研究以确定可能受益于无症状性 CHD 额外检查的糖尿病患者的潜在亚组。

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Impact of subclinical atherosclerosis on cardiovascular disease events in individuals with metabolic syndrome and diabetes: the multi-ethnic study of atherosclerosis.代谢综合征和糖尿病患者亚临床动脉粥样硬化对心血管疾病事件的影响:动脉粥样硬化多民族研究。
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