Department of Anaesthesia and Intensive Care, University Hospital Hamburg, Hamburg, Germany.
Reg Anesth Pain Med. 2012 May-Jun;37(3):318-24. doi: 10.1097/AAP.0b013e31825051f3.
Modern-day local anesthesia began in 1884 with a discovery by a young unknown ophthalmologist from Vienna named Carl Koller, who placed a cocaine solution on the cornea, thus producing insensibility. The news of his discovery spread throughout the world in less than a month. "Not surprisingly," a controversial priority discussion emerged. There is little information about this "dark side" of Koller's discovery and only sparse data about the personalities involved in this controversy. In addition, Carl Koller's decision to leave Vienna is also surrounded in secrecy. The story surrounding the revelation of the local anesthetic effect of cocaine and the personalities involved is fascinating and relatively unknown.
现代局部麻醉始于 1884 年，维也纳一位不知名的年轻眼科医生卡尔·科勒（Carl Koller）的一项发现，他将可卡因溶液置于角膜上，从而产生了麻木感。他的发现消息在不到一个月的时间里传遍了全世界。“毫不奇怪”，出现了一场具有争议的优先权讨论。关于科勒的这一发现的“阴暗面”几乎没有信息，而且涉及这一争议的人物的数据也很少。此外，卡尔·科勒离开维也纳的决定也笼罩在神秘之中。可卡因局部麻醉作用的揭示以及相关人物的故事引人入胜，却鲜为人知。
