State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, P. R. China, and Graduate School of Chinese Academy of Sciences, Beijing 100039, P. R. China.
Org Lett. 2012 May 18;14(10):2524-7. doi: 10.1021/ol3008149. Epub 2012 Apr 27.
Aphanamixoid A (1), a limonoid with a new carbon skeleton, along with its biogenetically related limonoid aphanamixoid B (2), was isolated from the leaves and twigs of Aphanamixis polystachya . Their structures with the absolute stereochemistry were determined by spectroscopic analysis, X-ray crystallography and computational methods. The significant antifeedant activity of 1 against the generalist plant-feeding insect Helicoverpa armigera (EC50 = 0.015 μmol/cm(2)) suggested it may be a potent defensive component of A. polystachya.
阿法六驳醇 A（1），一种具有新型碳骨架的柠檬苦素，与其生物起源相关的柠檬苦素阿法六驳醇 B（2），从 Aphanamixis polystachya 的叶和小枝中分离得到。通过光谱分析、X 射线晶体学和计算方法确定了它们的结构和绝对立体化学。化合物 1 对多食性植食性昆虫棉铃虫（EC50=0.015 μmol/cm(2)）具有显著的拒食活性，表明它可能是 A. polystachya 的一种潜在防御成分。
