Child Development Laboratory, Department of Human Development, University of Maryland, MD 20742-1131, USA.
Brain Cogn. 2012 Aug;79(3):181-7. doi: 10.1016/j.bandc.2012.02.013. Epub 2012 Apr 28.
The neural correlates of cognitive control for typically developing 9-year-old children were examined using dense-array ERPs and estimates of cortical activation (LORETA) during a go/no-go task with two conditions: a neutral picture condition and an affectively charged picture condition. Activation was estimated for the entire cortex after which data were exported for four regions of interests (ROIs): ventrolateral prefrontal cortex (VLPFC), dorsal anterior cingulate cortex (dACC), dorsolateral prefrontal cortex (DLPFC), and orbitofrontal/ventromedial prefrontal cortex (OFC/VMPFC). Results revealed faster reaction times, greater N2 activation, and greater prefrontal activation for the affectively charged picture condition than the neutral picture condition. The findings are discussed in reference to the impact of affective stimuli on recruitment of specific brain regions involved in cognitive control.
使用密集型 ERP 和皮质激活估计(LORETA)研究了 9 岁正常发育儿童的认知控制的神经相关性,在一个 Go/No-Go 任务中有两种条件:中性图片条件和情感负荷图片条件。对整个皮质进行激活估计,然后将数据导出到四个感兴趣区域(ROI):腹外侧前额叶皮层(VLPFC)、背侧前扣带皮层(dACC)、背外侧前额叶皮层(DLPFC)和眶额/腹内侧前额叶皮层(OFC/VMPFC)。结果表明,情感负荷图片条件的反应时间更快,N2 激活更大,前额叶激活更大。研究结果讨论了情感刺激对参与认知控制的特定大脑区域的招募的影响。