Division of Reconstructive Surgery for Oral and Maxillofacial Region, Department of Tissue Regeneration and Reconstruction, Course for Oral Life Science, Niigata University Graduate School of Medical and Dental Sciences, Japan.
Int J Oral Maxillofac Surg. 2012 Jul;41(7):853-7. doi: 10.1016/j.ijom.2012.01.020. Epub 2012 Apr 30.
The aim of this study was to establish an objective method for quantitative evaluation of bone volume change after sinus augmentation. 11 sinuses in 9 patients were evaluated by computed tomography images taken before treatment (T0), and 3 months (T1) and at least 1 year (T2) after sinus augmentation. Based on the 3D digital subtraction technique, augmented bone images were extracted and bone volumes were calculated from voxel numbers of the extracted images. The mean augmented bone volumes at T1 and T2 were 2.46 cm3 and 1.85 cm3, respectively. These bone volume changes were statistically significant and the mean bone volume change ± SE was -24.8% ± 6.1%. Loss of augmented bone was observed in all except one of the patients. The correlation coefficient between bone volume change and elapsed time was -0.64, which was statistically significant and indicated that bone resorption progressed with elapse of time after sinus augmentation. The authors' method of analysis enabled visualization of augmented bone and objective assessment of bone volume change. Within the limited number of cases, the present investigation demonstrated a significant decrease in augmented bone volume between 3 and 23 months after surgery.
本研究旨在建立一种客观的方法，定量评估鼻窦提升后骨量的变化。9 名患者的 11 个鼻窦分别在治疗前（T0）、3 个月（T1）和至少 1 年（T2）时进行计算机断层扫描（CT）图像评估。基于三维数字减影技术，提取增强骨图像，并从提取图像的体素数量计算骨体积。T1 和 T2 时的平均增强骨体积分别为 2.46cm3 和 1.85cm3。这些骨量变化具有统计学意义，平均骨量变化±SE 为-24.8%±6.1%。除 1 例患者外，所有患者均观察到增强骨丢失。骨量变化与时间的相关系数为-0.64，具有统计学意义，表明鼻窦提升后随时间推移，骨质吸收进展。作者的分析方法能够可视化增强骨并客观评估骨量变化。在有限的病例数内，本研究表明术后 3 至 23 个月，增强骨量显著减少。
