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本文引用的文献

1
Genome characterization of clinical isolates of human cytomegalovirus by restriction enzyme analysis.
Med Lab Sci. 1983 Jan;40(1):81-3.
2
Restriction endonuclease analysis of cytomegalovirus deoxyribonucleic acid as an epidemiologic tool.
Pediatrics. 1982 Nov;70(5):717-21.
3
Use of restriction enzymes to investigate the source of a primary cytomegalovirus infection in a pediatric nurse.
Pediatrics. 1982 Nov;70(5):713-6.
4
Cytomegalovirus: genetic variation of viral genomes.巨细胞病毒：病毒基因组的遗传变异
Ann N Y Acad Sci. 1980;354:332-46. doi: 10.1111/j.1749-6632.1980.tb27976.x.
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Restriction enzyme analysis of human cytomegalovirus using DNA extracted from infected cells.
J Med Virol. 1984;14(4):313-22. doi: 10.1002/jmv.1890140404.
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Application of "Hirt supernatant" DNA to the molecular epidemiology of cytomegalovirus infections.“赫特上清液”DNA在巨细胞病毒感染分子流行病学中的应用。
J Clin Microbiol. 1984 Nov;20(5):1012-4. doi: 10.1128/jcm.20.5.1012-1014.1984.
7
Reliable identification of herpes simplex viruses by DNA restriction endonuclease analysis with EcoRI.通过用EcoRI进行DNA限制性内切酶分析来可靠鉴定单纯疱疹病毒。
Sex Transm Dis. 1984 Apr-Jun;11(2):85-90. doi: 10.1097/00007435-198404000-00007.
8
An illustrated guide to the structure of the human cytomegalovirus genome and a review of transcription data.人类巨细胞病毒基因组结构图解指南及转录数据综述
Prog Med Virol. 1986;33:99-133.
9
Molecular epidemiology of cytomegalovirus: evidence for viral transmission to parents from children infected at a day care center.巨细胞病毒的分子流行病学：日托中心感染儿童将病毒传播给父母的证据。
Pediatr Infect Dis. 1986 May-Jun;5(3):315-8.
10
Use of restriction endonuclease digestion to analyze strains of human cytomegalovirus isolated concurrently from an immunocompetent heterosexual man.使用限制性内切酶消化法分析从一名免疫功能正常的异性恋男性身上同时分离出的人巨细胞病毒毒株。
J Infect Dis. 1986 Jul;154(1):167-8. doi: 10.1093/infdis/154.1.167.

人巨细胞病毒基因组特定区域在体外传代过程中的修饰

Modification of specific regions of the human cytomegalovirus genome during in vitro passage.

作者信息

Hamelin C, Dion M

机构信息

Centre de recherche en virologie, Institut Armand-Frappier, Laval-des-Rapides, Quebec.

出版信息

Can J Infect Dis. 1990 Summer;1(2):48-50. doi: 10.1155/1990/185934.

DOI:10.1155/1990/185934
PMID:22553439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3327962/
Abstract

Different regions of the human cytomegalovirus strain AD-169 DNA molecule were tested for stability using cloned Hind III fragments. Results indicate that insertion, deletion and/or rearrangement of nucleotide sequences occur at a relatively high frequency in all parts of the human cytomegalovirus genome during in vitro passage.

摘要

使用克隆的Hind III片段对人巨细胞病毒AD - 169株DNA分子的不同区域进行稳定性测试。结果表明，在体外传代过程中，人巨细胞病毒基因组的所有部分核苷酸序列的插入、缺失和/或重排都以相对较高的频率发生。