341例渗出性年龄相关性黄斑变性患者的激光治疗
Laser treatment in 341 patients with exudative age-related macular degeneration.
作者信息
Atmaca Leyla, Idil Aysun, Atmaca-Sönmez Pelin
机构信息
Department of Ophthalmology, Private Practice, Ankara, Turkey.
出版信息
Int J Ophthalmol. 2011;4(1):73-7. doi: 10.3980/j.issn.2222-3959.2011.01.17. Epub 2011 Feb 18.
AIM
To document the prognosis of laser treatment in patients with exudative age-related macular degeneration (AMD).
METHODS
Efficacy of the intervention was evaluated using a before-after method.
RESULTS
A total of 392 eyes of 341 patients with exudative AMD were examined. 77.6% had choroideal neovascularisation (CNV). Before the use of indocyanine green (ICG) angiography, occult CNV was detected in only 1.8% of the eyes, but after the use of ICG angiography, this increased to 19.5% (P<0.001). Of the 349 eyes which were followed up, visual acuity had remained stable in 68.2%. There was a statistically significant relationship between the localization of lesion and visual acuity changes on pre- and post-laser treatment (P<0.001). Also there was a statistically significant relationship between the localization of lesion and recurrence (P<0.05). The recurrence was less in subfoveal lesions than that in juxtafoveal and extrafoveal lesions.
CONCLUSION
ICG angiography is highly important in the treatment of occult CNV.
目的
记录激光治疗渗出性年龄相关性黄斑变性（AMD）患者的预后情况。
方法
采用前后对比法评估干预措施的疗效。
结果
共检查了341例渗出性AMD患者的392只眼。77.6%有脉络膜新生血管（CNV）。在使用吲哚菁绿（ICG）血管造影之前，仅1.8%的眼睛检测到隐匿性CNV，但使用ICG血管造影后，这一比例增至19.5%（P<0.001）。在接受随访的349只眼中，68.2%的视力保持稳定。激光治疗前后病变部位与视力变化之间存在统计学显著关系（P<0.001）。病变部位与复发之间也存在统计学显著关系（P<0.05）。黄斑中心凹下病变的复发率低于黄斑中心凹旁和黄斑中心凹外病变。
结论
ICG血管造影在隐匿性CNV的治疗中非常重要。
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