Division of Allergology, Immunology and Rhumatology, Department of Paediatrics, University Hospital Center and University of Lausanne, Lausanne, Switzerland.
Pediatr Allergy Immunol. 2012 Aug;23(5):412-9. doi: 10.1111/j.1399-3038.2012.01310.x. Epub 2012 May 3.
Food allergy in children significantly affects their quality of life. Its impact can be analyzed by quality of life questionnaires.
The aim of our study was to validate the French version of disease-specific questionnaires and to evaluate the quality of life in children with IgE-mediated food allergy.
Two validated food allergy-specific questionnaires for quality of life, the parent's and children's forms (FAQLQ-PF and FAQLQ-CF), were translated from English to French and submitted to children with food allergy and their parents. Questionnaires were analyzed in terms of emotional impact, food anxiety, and social and food limitations. NCT 01480427.
Sixty-two parents of children aged 0-12 yrs answered the FAQLQ-PF, and 32 children aged 8-12 yrs the FAQLQ-CF. Construct validity of both questionnaires was assessed by correlation between the FAQLQs and FAIM (r = 0.85 and 0.84, respectively). Both FAQLQs had good internal consistency (Cronbach's α = 0.748 and 0.67, respectively). Young children (0-3 yrs old) showed better quality of life scores than older children (FAQLQ-PF global score: p = 0.02). Worse scores were also shown among children with previous severe systemic reactions (FAQLQ-PF global score: p = 0.039), the ones with an allergic mother (FAQLQ-PF global score: p = 0.002), or allergic siblings (FAQLQ-PF emotional impact score: p = 0.034), the ones with multiple food allergy (more than 1 food) (FAQLQ-PF anxiety score: p = 0.04) and among the girls (FAQLQ-CF global score: p = 0.031).
Older children, the ones with severe systemic reactions, or with mothers or siblings also affected by allergies, as well as girls, and children with multiple food allergies show worse quality of life scores.
儿童食物过敏会显著影响其生活质量。可通过生活质量问卷进行分析。
本研究旨在验证特定于食物过敏的问卷的法语版本，并评估 IgE 介导的食物过敏儿童的生活质量。
我们将两种经过验证的食物过敏特异性生活质量问卷（父母版和儿童版，即 FAQLQ-PF 和 FAQLQ-CF）从英文翻译为法文，并提交给食物过敏儿童及其父母。从情绪影响、食物焦虑、社会和食物限制等方面分析问卷。NCT01480427。
62 名 0-12 岁儿童的父母回答了 FAQLQ-PF，32 名 8-12 岁儿童回答了 FAQLQ-CF。通过 FAQLQs 与 FAIM 之间的相关性评估了两种问卷的结构效度（r 值分别为 0.85 和 0.84）。两种 FAQLQ 均具有良好的内部一致性（Cronbach's α 值分别为 0.748 和 0.67）。年龄较小（0-3 岁）的儿童生活质量评分优于年龄较大的儿童（FAQLQ-PF 总体评分：p=0.02）。有既往严重全身性反应的儿童（FAQLQ-PF 总体评分：p=0.039）、有过敏母亲的儿童（FAQLQ-PF 总体评分：p=0.002）、有过敏兄弟姐妹的儿童（FAQLQ-PF 情绪影响评分：p=0.034）、有多种食物过敏（一种以上食物）的儿童（FAQLQ-PF 焦虑评分：p=0.04）和女孩（FAQLQ-CF 总体评分：p=0.031）的评分也较差。
年龄较大的儿童、有严重全身性反应的儿童、有过敏母亲或兄弟姐妹的儿童、女孩以及有多种食物过敏的儿童的生活质量评分较差。
