经典喉罩置入的诱导：小剂量芬太尼有效吗？
Induction for classic laryngeal mask airway insertion: Does low-dose fentanyl work?
作者信息
Dutt Akanksha, Joad Anjum Khan, Sharma Mamta
机构信息
Department of Anesthesiology, Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, India.
出版信息
J Anaesthesiol Clin Pharmacol. 2012 Apr;28(2):210-3. doi: 10.4103/0970-9185.94877.
Abstract
BACKGROUND
Laryngeal mask airway (LMA) insertion requires an optimal balance of anesthesia. Propofol with different opioids is a preferred combination. Two doses of fentanyl were compared for the efficacy and side effects.
MATERIALS AND METHODS
96 patients were randomly distributed into F(1) (fentanyl 1 mcg/kg) and F(2) (fentanyl 2 mcg/kg) groups. The conditions for LMA insertion, hemodynamic profile, bronchoscopic view, and incidence of sore throat were compared.
RESULT
There was no statistically significant difference in any parameter in the two groups except for a significant fall in systolic and mean arterial pressure in F(2) group.
CONCLUSION
Both doses of fentanyl (1 and 2 mcg/kg) provide comparable insertion conditions for LMA. Fentanyl in the lower dose provides a more stable hemodynamic profile.
摘要
背景
喉罩置入需要麻醉达到最佳平衡。丙泊酚与不同阿片类药物联合是一种优选组合。比较了两种剂量芬太尼的疗效和副作用。
材料与方法
96例患者随机分为F(1)组（芬太尼1微克/千克）和F(2)组（芬太尼2微克/千克）。比较喉罩置入条件、血流动力学参数、支气管镜视野及咽痛发生率。
结果
两组在任何参数上均无统计学显著差异，但F(2)组收缩压和平均动脉压显著下降。
结论
两种剂量的芬太尼（1和2微克/千克）为喉罩置入提供了相当的条件。较低剂量的芬太尼血流动力学更稳定。
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