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菲律宾蛤仔和缢蛏暴露在镉环境下的毒理学效应和生物积累模式。

Ruditapes decussatus and Ruditapes philippinarum exposed to cadmium: toxicological effects and bioaccumulation patterns.

机构信息

CBC, Departamento de Biologia, Universidade de Aveiro, Portugal.

出版信息

Comp Biochem Physiol C Toxicol Pharmacol. 2012 Aug;156(2):80-6. doi: 10.1016/j.cbpc.2012.04.004. Epub 2012 Apr 27.

Abstract

Since differences in metal accumulation may exist between bivalve species, the aim of this study was to assess the impact of cadmium (Cd) on Ruditapes decussatus and Ruditapes philippinarum. For this, the Cd accumulation, mortality rates and biochemical responses were analysed in the two species after 5days of exposure, under laboratory-controlled conditions. The concentration of Cd that caused 50% of mortality on clams was two-times higher in R. decussatus than in R. philippinarum. For both species, higher percentage (84.5-98.2%) of the Cd was in the insoluble fraction, but the Cd concentration in solution was 3 to 8 times higher in R. decussatus. Nevertheless, R. philippinarum presented higher oxidative stress and higher CAT activity. The paradox observed between the two clams can be explained by the higher capacity of R. decussatus to increase the expression of MTs when exposed to Cd.

摘要

由于双壳贝类物种之间可能存在金属积累的差异,因此本研究旨在评估镉(Cd)对褶牡蛎和菲律宾蛤仔的影响。为此,在实验室控制条件下,对两种物种在暴露 5 天后的 Cd 积累、死亡率和生化反应进行了分析。导致蛤死亡率达到 50%的 Cd 浓度在褶牡蛎中的含量是菲律宾蛤仔的两倍。对于这两个物种,较高比例(84.5-98.2%)的 Cd 存在于不溶性部分,但在褶牡蛎中,Cd 在溶液中的浓度是菲律宾蛤仔的 3 至 8 倍。然而,菲律宾蛤仔表现出更高的氧化应激和更高的 CAT 活性。这两种蛤之间观察到的矛盾可以用褶牡蛎在暴露于 Cd 时增加 MTs 表达的能力更高来解释。

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