Nat Cell Biol. 2012 May 30;14(6):559-61. doi: 10.1038/ncb2509.
The diverse nature of eukaryotic centromere structure has led to a prevailing view that the kinetochore-chromatin interface is fundamentally different in distinct species. Two studies now challenge this dogma with the identification of budding yeast homologues of the vertebrate centromere DNA-binding proteins CENP-T and CENP-W.
真核生物着丝粒结构的多样性导致了一种流行观点，即不同物种的动粒-染色质界面在根本上是不同的。现在有两项研究通过鉴定脊椎动物着丝粒 DNA 结合蛋白 CENP-T 和 CENP-W 的芽殖酵母同源物挑战了这一教条。
