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华盛顿金县男男性行为者中的艾滋病毒检测间隔。

HIV intertest interval among MSM in King County, Washington.

机构信息

Department of Epidemiology, University of Washington, Seattle, WA 98104, USA.

出版信息

Sex Transm Infect. 2013 Feb;89(1):32-7. doi: 10.1136/sextrans-2011-050470. Epub 2012 May 5.

DOI:10.1136/sextrans-2011-050470
PMID:22563016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3465512/
Abstract

OBJECTIVES

The authors examined temporal trends and correlates of HIV testing frequency among men who have sex with men (MSM) in King County, Washington.

METHODS

The authors evaluated data from MSM testing for HIV at the Public Health-Seattle & King County (PHSKC) STD Clinic and Gay City Health Project (GCHP) and testing history data from MSM in PHSKC HIV surveillance. The intertest interval (ITI) was defined as the number of days between the last negative HIV test and the current testing visit or first positive test. Correlates of the log(10)-transformed ITI were determined using generalised estimating equations linear regression.

RESULTS

Between 2003 and 2010, the median ITI among MSM seeking HIV testing at the STD Clinic and GCHP were 215 (IQR: 124-409) and 257 (IQR: 148-503) days, respectively. In multivariate analyses, younger age, having only male partners and reporting ≥10 male sex partners in the last year were associated with shorter ITIs at both testing sites (p<0.05). Among GCHP attendees, having a regular healthcare provider, seeking a test as part of a regular schedule and inhaled nitrite use in the last year were also associated with shorter ITIs (p<0.001). Compared with MSM testing HIV negative, MSM newly diagnosed with HIV had longer ITIs at the STD Clinic (median of 278 vs 213 days, p=0.01) and GCHP (median 359 vs 255 days, p=0.02).

CONCLUSIONS

Although MSM in King County appear to be testing at frequent intervals, further efforts are needed to reduce the time that HIV-infected persons are unaware of their status.

摘要

目的

作者研究了华盛顿州金县男男性行为者(MSM)艾滋病毒检测频率的时间趋势和相关因素。

方法

作者评估了在公共卫生-西雅图和金县(PHSKC)性传播疾病(STD)诊所和同性恋城市健康项目(GCHP)进行 HIV 检测的 MSM 检测数据,以及 PHSKC HIV 监测中 MSM 的检测史数据。检测间隔(ITI)定义为最后一次阴性 HIV 检测和当前检测访问或首次阳性检测之间的天数。使用广义估计方程线性回归确定对数(10)转换的 ITI 的相关因素。

结果

在 2003 年至 2010 年间,在 STD 诊所和 GCHP 寻求 HIV 检测的 MSM 的中位 ITI 分别为 215(IQR:124-409)和 257(IQR:148-503)天。在多变量分析中,年龄较小、仅有男性伴侣以及报告在过去一年中有≥10 名男性性伴侣与两个检测点的 ITI 较短相关(p<0.05)。在 GCHP 参与者中,有常规医疗保健提供者、定期预约检测和在过去一年中使用吸入亚硝酸酯也与 ITI 较短相关(p<0.001)。与 HIV 检测阴性的 MSM 相比,新诊断为 HIV 的 MSM 在 STD 诊所(中位数 278 比 213 天,p=0.01)和 GCHP(中位数 359 比 255 天,p=0.02)的 ITI 更长。

结论

尽管金县的 MSM 似乎经常进行检测,但仍需要进一步努力减少 HIV 感染者不知道自己状况的时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/733a/3465512/4f5e173eeee6/nihms387955f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/733a/3465512/b5d023c82f1d/nihms387955f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/733a/3465512/4f5e173eeee6/nihms387955f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/733a/3465512/b5d023c82f1d/nihms387955f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/733a/3465512/4f5e173eeee6/nihms387955f2.jpg

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