Tryfon Stavros, Parisis Valantis, Ioannis Kakoulidis, Saroglou Maria, Leonidas Sakkas, Despina Dimopoulou, Asterios Karagyannis, Alexandros Garyfallos
1st Pulmonary Clinic, General Hospital "G. Papanikolaou"
Clin Med Insights Case Rep. 2012;5:43-8. doi: 10.4137/CCRep.S9227. Epub 2012 Apr 23.
We present the case of a 58-year-old woman with a renin secreting typical bronchopulmonary carcinoid. This patient showed hypotension, constipation and fatigue due to extensive hypokaliemia (K =1.9 meq/L). Aldosterone (102.7 ng/100 mL) and renin (46 ng/mL) were excessively elevated at that time, but cortisol level was normal. Routine chest roentgenography and computed tomography revealed a nodular lesion in the upper left lung lobe, which was suspicious for a neurosecretory pulmonary tumor. The final diagnosis was made by using bronchoscopic procedures and the histologically diagnosis was compatible as a typical pulmonary carcinoid. The tumor was resected curatively, and the renin and aldosterone level became normal. A year after the patient looks healthy.
我们报告一例58岁患有分泌肾素的典型支气管肺类癌的女性病例。该患者因严重低钾血症(血钾=1.9毫当量/升)出现低血压、便秘和疲劳。当时醛固酮(102.7纳克/100毫升)和肾素(46纳克/毫升)过度升高,但皮质醇水平正常。常规胸部X线检查和计算机断层扫描显示左上肺叶有一个结节性病变,怀疑是神经分泌性肺肿瘤。通过支气管镜检查做出了最终诊断,组织学诊断为典型的肺类癌。肿瘤被根治性切除,肾素和醛固酮水平恢复正常。一年后患者看起来很健康。