Shibasaki M, Hori T, Shimizu T, Isoyama S, Takeda K, Takita H
Department of Pediatrics, University of Tsukuba, Japan.
Ann Allergy. 1990 Dec;65(6):489-95.
The relationship between sensitization to common allergens and the development of asthma and seasonal allergic rhinitis (SAR) was investigated in a total of 419 schoolchildren in a farming community where allergens of both Dermatophagoides farinae (Df) and orchard grass (OG) pollen predominate. Twelve subjects (2.9%) were found to have asthma and 35 subjects (8.4%) SAR. There was no significant association between occurrences of asthma and SAR. The incidence of asthma correlated with DF-specific IgE levels but not with OG-specific IgE levels, whereas that of SAR correlated with OG-specific IgE levels but not with Df-specific IgE levels. No significant correlation was detected between IgE antibody levels against Df and OG. These results suggest that asthma occurs independently of SAR.
在一个粉尘螨（Df）和果园草（OG）花粉过敏原占主导的农业社区，对419名学童进行了常见过敏原致敏与哮喘及季节性变应性鼻炎（SAR）发病关系的调查。发现12名受试者（2.9%）患有哮喘，35名受试者（8.4%）患有SAR。哮喘和SAR的发病之间没有显著关联。哮喘发病率与粉尘螨特异性IgE水平相关，而与果园草特异性IgE水平无关，而SAR发病率与果园草特异性IgE水平相关，与粉尘螨特异性IgE水平无关。针对粉尘螨和果园草的IgE抗体水平之间未检测到显著相关性。这些结果表明，哮喘独立于SAR发生。
