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脉冲染料激光治疗毛细血管畸形(葡萄酒色斑)的临床经验:初步报告。

Clinical experience with the pulsed-dye laser in the treatment of capillary malformations (port-wine stains): a preliminary report.

作者信息

Achauer B M, Vander Kam V M, Miller S R

机构信息

Plastic Surgery Division, Beckman Laser Institute, Orange, CA 92668.

出版信息

Ann Plast Surg. 1990 Nov;25(5):344-52. doi: 10.1097/00000637-199011000-00002.

DOI:10.1097/00000637-199011000-00002
PMID:2256647
Abstract

This preliminary report reviews a series of 70 patients treated with tunable-dye laser therapy for congenital capillary malformations (port-wine stains). Results were reviewed according to age and ethnic group of patients and color and anatomical location of malformations. Red birthmarks were most responsive to treatment in all age groups in all anatomical locations. Purple birthmarks were generally less responsive to laser treatment except in children, who responded well. Scarring and hypopigmentation were minimal (5.7% and 1%, respectively), even in nonwhite patients. Recommendations emerging from this study include testing of infants, as results may vary. Detrimental side effects are rare. A major goal in treating port-wine stains is to avoid both the progression of these lesions through life and the psychological complications that occur during early socialization years in childhood. Pulsed-dye laser treatment offers much promise in these areas.

摘要

这份初步报告回顾了70例接受可调染料激光治疗先天性毛细血管畸形(葡萄酒色斑)的患者。根据患者的年龄、种族以及畸形的颜色和解剖位置对结果进行了评估。在所有解剖位置的所有年龄组中,红色胎记对治疗的反应最为明显。紫色胎记通常对激光治疗反应较差,但儿童患者反应良好。即使在非白人患者中,瘢痕形成和色素减退也很少见(分别为5.7%和1%)。这项研究得出的建议包括对婴儿进行检测,因为结果可能会有所不同。有害的副作用很少见。治疗葡萄酒色斑的一个主要目标是避免这些病变在一生中的进展以及儿童早期社交阶段出现的心理并发症。脉冲染料激光治疗在这些方面有很大的前景。

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Clinical experience with the pulsed-dye laser in the treatment of capillary malformations (port-wine stains): a preliminary report.脉冲染料激光治疗毛细血管畸形(葡萄酒色斑)的临床经验:初步报告。
Ann Plast Surg. 1990 Nov;25(5):344-52. doi: 10.1097/00000637-199011000-00002.
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Lasers or light sources for treating port-wine stains.用于治疗葡萄酒色斑的激光或光源。
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引用本文的文献

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Use of reflectance spectrophotometry to predict the response of port wine stains to pulsed dye laser.使用反射分光光度法预测葡萄酒色斑对脉冲染料激光的反应。
Lasers Med Sci. 2014 Jan;29(1):225-30. doi: 10.1007/s10103-013-1317-2. Epub 2013 Apr 23.
2
Lasers for cutaneous congenital vascular lesions: a comprehensive overview and update.激光治疗皮肤先天性血管病变:全面综述与更新。
Lasers Med Sci. 2013 Jul;28(4):1197-204. doi: 10.1007/s10103-012-1220-2. Epub 2012 Oct 24.
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An overview of clinical and experimental treatment modalities for port wine stains.
鲜红斑痣的临床和实验治疗方法概述。
J Am Acad Dermatol. 2012 Aug;67(2):289-304. doi: 10.1016/j.jaad.2011.11.938. Epub 2012 Feb 3.
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Pulsed dye laser double-pass treatment of patients with resistant capillary malformations.脉冲染料激光双程治疗耐药性毛细血管畸形患者。
Lasers Med Sci. 2011 Jul;26(4):487-92. doi: 10.1007/s10103-011-0913-2. Epub 2011 Apr 8.