Wegiera Magdalena, Smolarz Helena D, Jedruch Marcin, Korczak Magdalena, Koproń Kamila
Department of Pharmaceutical Botany, Medical University, 20-093 Lublin, Poland.
Acta Pol Pharm. 2012 Mar-Apr;69(2):263-8.
In this study the in vitro cytotoxic properties of ethanol extracts from the herbs, inflorescents and roots of selected Asteraceae species: Arctium lappa, Artemisia absinthium, Calendula officinalis, Centaurea cyanus, Tanacetum vulgare and Tragopogon pratensis on J-45.01 human acute T leukemia cell line was examined. All tested samples possess antileukemic properties and induce cells death via apoptosis. The correlation between antileukemic activity and total polyphenol content was determined.
在本研究中，检测了菊科选定物种牛蒡、苦艾、金盏花、矢车菊、艾菊和草地婆罗门参的叶、花和根的乙醇提取物对J-45.01人急性T白血病细胞系的体外细胞毒性。所有测试样品均具有抗白血病特性，并通过凋亡诱导细胞死亡。测定了抗白血病活性与总多酚含量之间的相关性。
