新型对比增强影像胶囊内镜在评估息肉病综合征中的作用。
Role of enhanced visibility in evaluating polyposis syndromes using a newly developed contrast image capsule endoscope.
机构信息
Tokyo Saiseikai Central Hospital, Tokyo, Japan.
出版信息
Gut Liver. 2012 Apr;6(2):218-22. doi: 10.5009/gnl.2012.6.2.218. Epub 2012 Apr 17.
BACKGROUND/AIMS: A flexible spectral imaging color enhancement system was installed in new capsule software for video capsule endoscopy. Contrast image capsule endoscopy (CICE) is a novel technology using light-emitting diodes selected for the main absorption range of hemoglobin. We assessed the feasibility and diagnostic effi cacy for small bowel surveillance in patients with polyposis syndromes.
METHODS
Six patients with polyposis syndromes, four with familial adenomatous polyposis and one each with Cowden syndrome (CS) and Cronkhite-Canada syndrome (CCS) were examined using CICE. We conducted three evaluations to assess the effect on the numbers of the detected polyps; compare polyp diagnostic rates between adenoma and hamartoma; and assess polyp visibility.
RESULTS
The numbers of detected polyps and diagnostic accuracy did not differ signifi cantly between pre-contrast and contrast images. However, 50% of the adenomatous polyps displayed enhanced visibility on contrast images. CICE contrast images exhibited clearly demarcated lesions and improved the visibility of minute structures of adenomatous polyps. Hamartomatous polyp micro-structures in patients with CS and CCS were more clearly visualized on contrast than pre-contrast images.
CONCLUSIONS
CICE is an effective tool for enhancing the visibility of polyps in patients with polyposis syndrome.
背景/目的：在新款胶囊内镜视频软件中安装了一种灵活的光谱成像彩色增强系统。对比显色胶囊内镜（CICE）是一种使用发光二极管的新技术，这些二极管的选择基于血红蛋白的主要吸收范围。我们评估了其在息肉综合征患者的小肠监测中的可行性和诊断效果。
方法
6 例息肉综合征患者（4 例家族性腺瘤性息肉病，1 例 Cowden 综合征和 1 例 Cronkhite-Canada 综合征）接受 CICE 检查。我们进行了三次评估，以评估对检测到的息肉数量的影响；比较腺瘤和错构瘤之间的息肉诊断率；评估息肉可见度。
结果
增强前后图像的息肉检出数量和诊断准确率无显著差异。然而，50%的腺瘤性息肉在对比图像上的可视性增强。CICE 对比图像显示出清晰的边界病变，并改善了腺瘤性息肉的微小结构的可视性。CS 和 CCS 患者的错构瘤性息肉微结构在对比图像上比增强前图像更清晰。
结论
CICE 是增强息肉综合征患者息肉可视性的有效工具。
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