无线胶囊内镜在家族性腺瘤性息肉病中小肠息肉的检测。
Wireless capsule endoscopy in detecting small-intestinal polyps in familial adenomatous polyposis.
机构信息
Department of Endoscopy and Motility Unit, Central Hospital, Ethnikis Aminis 41, 54635, Thessaloniki, Greece.
出版信息
World J Gastroenterol. 2009 Dec 28;15(48):6075-9. doi: 10.3748/wjg.15.6075.
Abstract
AIM
To detect the prevalence of small bowel polyps by wireless capsule endoscopy (WCE) in patients with familial adenomatous polyposis (FAP).
METHODS
We examined prospectively 14 patients with FAP to assess the location, size and number of small-intestinal polyps. Patients' age, sex, years of observation after surgery, type of surgery, duodenal polyps and colorectal cancer at surgery were analyzed.
RESULTS
During WCE, polyps were detected in 9/14 (64.3%) patients. Duodenal adenomatous polyps were found in nine (64.3%) patients, and jejunal and ileal polyps in seven (50%) and eight (57.1%), respectively. The Spigelman stage of duodenal polyposis was associated with the presence of jejunal and ileal polyps. Identification of the ampulla of Vater was not achieved with WCE. Importantly, the findings of WCE had no immediate impact on the further clinical management of FAP patients. No procedure-related complications were observed in the patients.
CONCLUSION
WCE is a promising noninvasive new method for the detection of small-intestinal polyps. Further investigation is required to determine which phenotype of FAP is needed for surveillance with WCE.
摘要
目的
通过无线胶囊内镜（WCE）检测家族性腺瘤性息肉病（FAP）患者的小肠息肉患病率。
方法
我们前瞻性检查了 14 例 FAP 患者，以评估小肠息肉的位置、大小和数量。分析了患者的年龄、性别、手术后观察年限、手术类型、十二指肠息肉和手术时的结直肠癌。
结果
在 WCE 检查中，9/14（64.3%）例患者发现了息肉。9 例（64.3%）患者发现了十二指肠腺瘤性息肉，7 例（50%）和 8 例（57.1%）患者分别发现了空肠和回肠息肉。十二指肠息肉的 Spigelman 分期与空肠和回肠息肉的存在有关。WCE 未能识别 Vater 壶腹。重要的是，WCE 的发现对 FAP 患者的进一步临床管理没有直接影响。患者未出现与检查相关的并发症。
结论
WCE 是一种有前途的非侵入性新方法，可用于检测小肠息肉。需要进一步研究确定哪种 FAP 表型需要用 WCE 进行监测。
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