Nwizu E N, Iliyasu Z, Ibrahim S A, Galadanci H S
Department of Obstetrics and Gynaecology, Federal Medical Centre, Azare, Bauchi State, Nigeria.
Afr J Reprod Health. 2011 Dec;15(4):33-41.
Anaemia in pregnancy still causes significant maternal morbidity and mortality in the developing countries including Nigeria. The burden and underlying factors are varied even within countries. We studied the prevalence of anaemia at booking and underlying factors in a teaching hospital in northern Nigeria. Using the capillary technique and blood film, the packed cell volume (PCV) and red cell morphology of 300 pregnant women was determined. Additional information was obtained on sociodemographic characteristics, obstetric and past medical history using an interviewer administered questionnaire. Of the 300 pregnant women studied, 51 (17%) [95% Confidence Interval (CI)=12.9%-21.7%] were anaemic. Specifically, 12.7% and 4.3% of the women had mild and moderate anaemia respectively. Blood film of 74.5%, 15.7% and 11.8% anaemic women showed normochromic normocytic, haemolytic and microcytic hypochromic pictures respectively. Low educational attainment [Adjusted Odds Ratio (AOR)=2.13], being single or divorced [AOR=2.02], high parity [AOR=2.06], late booking [AOR=2.71] and short intervals between pregnancies [AOR=2.37] were significant predictors of anaemia in pregnancy. The high prevalence of anaemia in pregnancy related to low educational and economic status especially among women with background obstetric risk factors calls for vigilance, sustained health education and chemoprophylaxis for pregnant women.
在包括尼日利亚在内的发展中国家,妊娠期贫血仍然导致孕产妇出现严重的发病和死亡情况。即使在同一个国家内,贫血的负担和潜在因素也各不相同。我们研究了尼日利亚北部一家教学医院孕妇在初次产检时的贫血患病率及其潜在因素。采用毛细血管技术和血涂片,测定了300名孕妇的红细胞压积(PCV)和红细胞形态。通过访谈问卷获取了有关社会人口学特征、产科病史和既往病史的其他信息。在研究的300名孕妇中,51名(17%)[95%置信区间(CI)=12.9%-21.7%]患有贫血。具体而言,分别有12.7%和4.3%的女性患有轻度和中度贫血。贫血女性的血涂片分别显示正细胞正色素性、溶血性和小细胞低色素性图像的比例为74.5%、15.7%和11.8%。低教育程度[调整优势比(AOR)=2.13]、单身或离异[AOR=2.02]、高孕次[AOR=2.06]、产检延迟[AOR=2.71]以及妊娠间隔短[AOR=2.37]是妊娠期贫血的显著预测因素。妊娠期贫血的高患病率与低教育和经济状况有关,尤其是在有产科危险因素背景的女性中,这需要对孕妇保持警惕、持续开展健康教育并进行化学预防。