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在英语人群中,喉咽反流的流行率。

The prevalence of laryngopharyngeal reflux in the English population.

机构信息

Department of Otolaryngology Head and Neck Surgery, Queen's Medical Centre, Nottingham, UK.

出版信息

Eur Arch Otorhinolaryngol. 2012 Oct;269(10):2219-25. doi: 10.1007/s00405-012-2028-1. Epub 2012 May 11.

Abstract

Although symptoms of laryngopharyngeal reflux (LPR) symptoms are commonly seen in the ENT clinic, their aetiology and prevalence in the population remain unknown. Lifestyle changes have been seen to be effective in symptom relief. We aimed to establish the prevalence of these symptoms and identify any associated factors. Pseudo-random sampling was performed on 2,000 adults that were sent a validated questionnaire containing the Reflux Symptom Index (RSI) and questions on their health and lifestyle. 45.8 % of the 378 responders were male. The mean RSI was 8.3. 30 % had an RSI of more than 10, of which 75 % had symptoms of gastro-oesophageal reflux disease (r = 0.646 at p = 0.01). Patients with depression and irritable bowel syndrome are more likely to have LPR symptoms. LPR symptoms are highly prevalent in the community and may be influenced significantly by the presence of gastro-oesophageal reflux, depression and irritable bowel syndrome.

摘要

尽管喉咽反流(LPR)症状在耳鼻喉科诊所中很常见,但它们的病因和人群患病率仍不清楚。生活方式的改变已被证明对缓解症状有效。我们旨在确定这些症状的患病率,并确定任何相关因素。我们对 2000 名成年人进行了伪随机抽样,向他们发送了一份经过验证的问卷,其中包含反流症状指数(RSI)和有关他们健康和生活方式的问题。378 名应答者中有 45.8%为男性。RSI 的平均值为 8.3。30%的人 RSI 大于 10,其中 75%的人有胃食管反流病症状(r = 0.646,p = 0.01)。患有抑郁症和肠易激综合征的患者更有可能出现 LPR 症状。LPR 症状在社区中非常普遍,可能受到胃食管反流、抑郁和肠易激综合征的显著影响。

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