Perelman-Karmon Mally, Kozlovsky Avital, Liloy Roman, Artzi Zvi
Department of Oral Sciences, School of Dental Medicine, State University of New York, Buffalo, New York, USA.
Int J Periodontics Restorative Dent. 2012 Aug;32(4):459-65.
The purpose of this study was to compare extraction sites augmented with bovine bone mineral (BBM) with and without resorbable membrane coverage. BBM particles were grafted in fresh human extraction sockets of 23 patients; in 12 of these patients, a guided tissue regeneration (GTR) membrane was applied. After 9 months of histomorphometric evaluation, cylindric hard tissue specimens were obtained. Percent bone area fractions (BAFs) of the crestal, middle, and apical sections from each specimen were calculated using the point-counting technique. Changes in values were compared. In sites augmented with BBM, the mean BAF ranged from 22.8% (coronal) to 36.3% (apical) compared to sites augmented with BBM and collagen membrane (35.2% [coronal] to 47% [apical]). Comparison between the different depths and the two groups showed a distinct increase in BAF from coronal to apical regions (P < .001). This pattern was observed in both groups (P < .001) and was significantly higher in the group augmented with BBM and collagen membrane (P < .05). In the immediate postextraction phase, BBM as a grafted biomaterial preserved the socket volume and enabled newly formed bone for future implant site preparation. The amount of the osseous fraction increased with GTR membrane.
本研究的目的是比较使用和不使用可吸收膜覆盖的牛骨矿物质（BBM）增强的拔牙位点。将BBM颗粒植入23例患者的新鲜人类拔牙窝中；其中12例患者应用了引导组织再生（GTR）膜。经过9个月的组织形态计量学评估后，获取圆柱形硬组织标本。使用点计数技术计算每个标本的嵴部、中部和根尖部的骨面积分数（BAF）百分比。比较数值变化。在使用BBM增强的位点，平均BAF范围为22.8%（冠部）至36.3%（根尖部），而使用BBM和胶原膜增强的位点为35.2%（冠部）至47%（根尖部）。不同深度和两组之间的比较显示，从冠部到根尖区域BAF有明显增加（P <.001）。两组均观察到这种模式（P <.001），且在使用BBM和胶原膜增强的组中显著更高（P <.05）。在拔牙后即刻阶段，BBM作为一种植入的生物材料保留了牙槽窝容积，并为未来的种植位点预备提供了新形成的骨。骨成分的量随着GTR膜而增加。
