Langenbucher A, Eppig T, Viestenz A, Seitz B, Müllner G, Schönherr U
Experimentelle Ophthalmologie, Universität des Saarlandes, Kirrberger Str. 100, 66421, Homburg (Saar), Deutschland.
Ophthalmologe. 2012 May;109(5):468-73. doi: 10.1007/s00347-012-2535-x.
The aim of the study was an assessment of refraction error after implantation of two types of hydrophobic acrylic intraocular lenses and derivation of customized IOL constants for the SRK II, SRK/T, Hoffer Q, Holladay 1 and Haigis formula.
The purpose of the present study was to analyze the refractive outcome of two hydrophobic acrylic intraocular lenses and to present a computerized calculation scheme for customization of lens-specific parameters provided by the lens manufacturers based on the refractive results of a surgeon or study center.
In this prospective monocentric study 100 consecutive cataract eyes were treated at the Eye Hospital of the Barmherzige Brüder (Compassionate Brothers) in Linz/Austria with a hydrophobic acrylic aspherical intraocular lens (Polytech Y10AS, n = 50) or a hydrophobic acrylic spherical intraocular lens (Hoya PC-60R, n = 50). The biometrical data were assessed preoperatively together with the refractive outcome 8-10 weeks after treatment in order to analyze the deviation of postoperative refraction (spherical equivalent) from target refraction (ΔREF) and to customize the lens constants for the SRK II, SRK/T, Hoffer Q, Holladay 1 and Haigis formula.
Based on this data set it could be demonstrated that using the lens constant provided by the manufacturer (ΔREF) the Polytech lens showed a systematic trend to myopia in contrast to the Hoya lens which ranged around zero. This trend could be compensated by selecting appropriate lens specific constants. For the Polytech/Hoya lens median lens constants of: A = 118.0/118.6 (SRK II), A = 117.9/118.6 (SRK/T), pACD = 4.8/5.1 (Hoffer Q), SF = 1.1/1.5 (Holladay I) and d = 4.2/4.6 (Haigis) were extracted and using linear regression a lens constant triplet for the Haigis formula of a(0) = 4.39, a(1) = 0.29, a(2) = 0.11/a0 = 4.73, a(1) = 0.30, a(2) = -0.01 could be derived.
Ophthalmic surgeons or surgical centers are encouraged to check (refractive) outcomes after cataract surgery permanently in terms of quality control. If a systematic trend in ΔREF could be extracted from the data set a customization of the lens-specific constants is recommended to eliminate systematic errors. Such customization is only valid for a dedicated environment (e.g. for one surgical center with standardized surgical techniques and measurement equipment) and cannot be generalized.
本研究旨在评估两种类型的疏水丙烯酸人工晶状体植入后的屈光不正，并推导适用于SRK II、SRK/T、霍弗Q、霍拉迪1和海吉斯公式的定制人工晶状体常数。
本研究的目的是分析两种疏水丙烯酸人工晶状体的屈光结果，并提出一种计算机化计算方案，以便根据外科医生或研究中心的屈光结果，定制由人工晶状体制造商提供的特定晶状体参数。
在这项前瞻性单中心研究中，奥地利林茨仁慈兄弟眼科医院连续对100例白内障患者的眼睛进行治疗，其中50例植入疏水丙烯酸非球面人工晶状体（宝利泰Y10AS），50例植入疏水丙烯酸球面人工晶状体（豪雅PC - 60R）。术前评估生物测量数据，并在治疗后8 - 10周评估屈光结果，以分析术后屈光（球镜等效度）与目标屈光的偏差（ΔREF），并定制适用于SRK II、SRK/T、霍弗Q、霍拉迪1和海吉斯公式的晶状体常数。
基于该数据集可以证明，使用制造商提供的晶状体常数（ΔREF）时，宝利泰晶状体呈现出近视的系统趋势，而豪雅晶状体的偏差范围接近零。通过选择合适的特定晶状体常数可以补偿这种趋势。提取了宝利泰/豪雅晶状体的中位数晶状体常数：A = 118.0/118.6（SRK II），A = 117.9/118.6（SRK/T），pACD = 4.8/5.1（霍弗Q），SF = 1.1/1.5（霍拉迪I），d = 4.2/4.6（海吉斯），并通过线性回归得出海吉斯公式的晶状体常数三元组：a(0) = 4.39，a(1) = 0.29，a(2) = 0.11/a0 = 4.73，a(1) = 0.30，a(2) = -0.01。
鼓励眼科医生或手术中心在质量控制方面持续检查白内障手术后的（屈光）结果。如果能从数据集中提取出ΔREF的系统趋势，建议定制特定晶状体常数以消除系统误差。这种定制仅适用于特定环境（例如具有标准化手术技术和测量设备的一个手术中心），不能一概而论。
