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中毒与临床毒理学:爱尔兰模式。

Poisonings and clinical toxicology: a template for Ireland.

机构信息

Beaumont Hospital, Dublin 9, Ireland.

出版信息

Ir J Med Sci. 2013 Mar;182(1):17-23. doi: 10.1007/s11845-012-0828-3. Epub 2012 May 13.

DOI:10.1007/s11845-012-0828-3
PMID:22581098
Abstract

BACKGROUND

Poisons information is accessed around the clock in the British Isles from six centres of which two are in Ireland at Dublin and Belfast accompanied by consultant toxicologist advisory service. The numbers of calls in Ireland are down to about 40 per day due to easy access to online data bases. Access to Toxbase, the clinical toxicology database of the National Poisons Information Service is available to National Health Service (NHS) health professionals and to Emergency Departments and Intensive Care units in the Republic of Ireland. There are 59 Toxbase users in the Republic of Ireland and 99 % of activity originates in Emergency Departments. All United States Poison Control Centres primarily use Poisindex which is a commercial database from Thomson Reuters.

RESULTS

Information on paracetamol, diazepam, analgesics and psycho-active compounds are the commonest queries. Data from telephone and computer accesses provide an indicator of future trends in both licit and illicit drug poisons which may direct laboratory analytical service developments. Data from National Drug-Related Deaths Index is the most accurate information on toxicological deaths in Ireland. Laboratory toxicology requirements to support emergency departments are listed.

CONCLUSIONS

Recommendations are made for a web-based open access Toxbase or equivalent; for a co-location of poisons information and laboratory clinical toxicology; for the establishment of a National Clinical Toxicology Institute for Ireland; for a list of accredited medical advisors in clinical toxicology; for multidisciplinary case conferences in complex toxicology cases for coroners; for the establishment of a national clinical toxicology referral out-patients service in Ireland.

摘要

背景

不列颠群岛的六个毒物信息中心提供 24 小时毒物信息服务,其中两个位于爱尔兰的都柏林和贝尔法斯特,并配备顾问毒理学家咨询服务。由于可以轻松访问在线数据库,爱尔兰的来电数量减少到每天约 40 个。国家毒物信息服务的临床毒理学数据库 Toxbase 可供国民保健服务(NHS)的医疗保健专业人员以及爱尔兰共和国的急诊部门和重症监护病房使用。爱尔兰共和国共有 59 个 Toxbase 用户,其中 99%的活动来自急诊部门。所有美国中毒控制中心主要使用来自汤森路透的商业数据库 Poisindex。

结果

对扑热息痛、地西泮、镇痛药和精神活性化合物的信息查询最为常见。电话和计算机访问提供了合法和非法药物中毒未来趋势的指标,这可能会指导实验室分析服务的发展。国家毒品相关死亡索引的数据是爱尔兰毒理学死亡最准确的信息。列出了支持急诊部门的实验室毒理学要求。

结论

建议建立基于网络的开放访问 Toxbase 或等效物;毒物信息和实验室临床毒理学的共同定位;为爱尔兰建立国家临床毒理学研究所;列出临床毒理学认可的医学顾问名单;为验尸官的复杂毒理学案例进行多学科案例会议;在爱尔兰建立国家临床毒理学转诊门诊服务。

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