Chiam Patrick
Eye Care Centre, Leighton Hospital, Crewe, Cheshire CW1 4QJ, UK.
Case Rep Ophthalmol Med. 2011;2011:507073. doi: 10.1155/2011/507073. Epub 2011 Dec 14.
Purpose. To report a case of granulomatous anterior uveitis caused by travoprost. Methods. Single observational case report. Results. A 71-year-old who was fit and healthy presented with bilateral granulomatous anterior uveitis 2 months after he was started on travoprost in both eyes. There was no past history of uveitis. Blood test and radiological investigation were unremarkable. Travoprost was stopped. The uveitis resolved on topical steroid treatment. A rechallenge with travoprost was attempted in one eye. The inflammation recurred in this eye only. This subsided with the cessation of travoprost alone without topical steroid. Conclusion. This is the first case report of travoprost causing granulomatous anterior uveitis. The uveitis recurred with a rechallenge. Changing the prostaglandin analogue to another topical treatment may be adequate to cease the inflammation.
目的。报告一例由曲伏前列素引起的肉芽肿性前葡萄膜炎病例。方法。单例观察病例报告。结果。一名71岁身体健康的男性在双眼开始使用曲伏前列素2个月后出现双侧肉芽肿性前葡萄膜炎。既往无葡萄膜炎病史。血液检查和影像学检查均无异常。停用曲伏前列素。葡萄膜炎经局部使用类固醇治疗后消退。对一只眼睛尝试重新使用曲伏前列素。仅该眼炎症复发。仅停用曲伏前列素后炎症消退，未使用局部类固醇。结论。这是曲伏前列素引起肉芽肿性前葡萄膜炎的首例病例报告。重新使用时炎症复发。将前列腺素类似物换为另一种局部治疗可能足以消除炎症。
