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2011 年在挪威采集的血清中,与甲型 H3N2 变异病毒发生交叉反应的抗体的年龄相关性流行率。

Age-dependent prevalence of antibodies cross-reactive to the influenza A(H3N2) variant virus in sera collected in Norway in 2011.

机构信息

Department of Virology, Norwegian Institute of Public Health, Oslo, Norway.

出版信息

Euro Surveill. 2012 May 10;17(19):20170.

PMID:22607964
Abstract

Antibody cross-reactivity to the influenza A(H3N2) variant virus recently reported in the United States, was investigated in Norwegian sera. Seroprevalence was 40% overall, and 71% in people born between 1977 and 1993. The most susceptible age groups were children and people aged around 50 years. The high immunity in young adults is likely to be due to strong priming infection with similar viruses in the 1990s. More research is needed to explain the poor immunity in 45–54 year-olds.

摘要

抗体对美国最近报告的甲型 H3N2 流感变异病毒的交叉反应性在挪威血清中进行了研究。总的血清阳性率为 40%,1977 年至 1993 年出生的人为 71%。最易感的年龄组是儿童和 50 岁左右的人群。年轻人的高免疫力可能是由于 20 世纪 90 年代类似病毒的强烈初始感染。需要进一步研究来解释 45-54 岁人群免疫力差的原因。

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