Division of Sleep Medicine, Harvard Medical School, Boston, MA 02215, USA.
Prog Neurobiol. 2012 Jul;98(1):82-98. doi: 10.1016/j.pneurobio.2012.05.003. Epub 2012 May 15.
This paper presents a theoretical review of rapid eye movement sleep with a special focus on pontine-geniculate-occipital waves and what they might tell us about the functional anatomy of sleep and consciousness. In particular, we review established ideas about the nature and purpose of sleep in terms of protoconsciousness and free energy minimization. By combining these theoretical perspectives, we discover answers to some fundamental questions about sleep: for example, why is homeothermy suspended during sleep? Why is sleep necessary? Why are we not surprised by our dreams? What is the role of synaptic regression in sleep? The imperatives for sleep that emerge also allow us to speculate about the functional role of PGO waves and make some empirical predictions that can, in principle, be tested using recent advances in the modeling of electrophysiological data.
本文对快速眼动睡眠进行了理论回顾，特别关注桥脑-膝状体-枕叶波以及它们可能告诉我们的关于睡眠和意识的功能解剖学信息。特别是，我们根据原意识和自由能最小化的观点，回顾了关于睡眠的本质和目的的既定观点。通过将这些理论观点结合起来，我们发现了一些关于睡眠的基本问题的答案：例如，为什么在睡眠期间体温调节会暂停？为什么睡眠是必要的？为什么我们不会对自己的梦境感到惊讶？突触回归在睡眠中的作用是什么？睡眠的必要性也让我们对 PGO 波的功能作用进行推测，并做出一些可以使用最近在电生理数据建模方面的进展进行测试的经验预测。
