Wong Rebecca K S, Brierley James, Brouwers Melissa
Curr Colorectal Cancer Rep. 2012 Jun;8(2):83-89. doi: 10.1007/s11888-012-0121-x. Epub 2012 Mar 13.
Evidence-based guidelines are important tools and common pathways for translating evidence into clinical practice. It is most urgently needed when significant heterogeneity in practice exist. Actively engaging opinion leaders in the process of evidence-based guidelines development is important for several reasons. These include allowing the collective views of the practice communities to be represented, resolving heterogeneity in practice through discussion, and allowing credible recommendations to be formulated. Most importantly, the process itself is a tool for facilitating dissemination and implementation. Recognizing the gap between practice pattern and guideline recommendations, and devising strategies to address it represent an important step toward maximizing concordance between guideline and practice. Evidence-based recommendations serve as important reference points, against which we can measure, debate, and innovate from.
循证指南是将证据转化为临床实践的重要工具和通用途径。当实践中存在显著异质性时，这一需求最为迫切。让意见领袖积极参与循证指南的制定过程很重要，原因有以下几点。这些原因包括使实践群体的集体观点得到体现，通过讨论解决实践中的异质性，并形成可信的建议。最重要的是，这个过程本身就是促进传播和实施的工具。认识到实践模式与指南建议之间的差距，并制定应对策略，是朝着使指南与实践达到最大程度一致迈出的重要一步。循证建议是重要的参考点，我们可以据此进行衡量、辩论和创新。
