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红色和红外低强度激光疗法治疗寻常痤疮的比较

Comparison of Red and Infrared Low-level Laser Therapy in the Treatment of Acne Vulgaris.

作者信息

Aziz-Jalali Mir Hadi, Tabaie Seyed Mehdi, Djavid Gholamreza Esmaeeli

机构信息

Department of Dermatology, Hazrat-e Rasool University Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Indian J Dermatol. 2012 Mar;57(2):128-30. doi: 10.4103/0019-5154.94283.

Abstract

BACKGROUND/PURPOSE: Acne vulgaris is a very prevalent skin disorder and remains a main problem in practice. Recently, phototherapy with various light spectrums for acne has been used. There are some evidences that low-level laser therapy (LLLT) has beneficial effect in the treatment of acne lesions. In this study, two different wavelengths of LLLT (630 and 890 nm) were evaluated in treatment of acne vulgaris.

MATERIALS AND METHODS

This study was a single-blind randomized clinical trial. Patients with mild to moderate acne vulgaris and age above 18 years and included were treated with red LLLT (630 nm) and infrared LLLT (890 nm) on the right and left sides of the face respectively, twice in a week for 12 sessions, and clinically assessed at baseline and weeks 2, 4, 6, and 8.

RESULTS

Twenty-eight patients were participated in this study. Ten weeks after treatment acne lesion were significantly decreased in the side treated by 630 nm LLLT (27.7±12.7 to 6.3±1.9) (P<0.001), but this decrease was not significant in the site treated by 890 nm LLLT (26.9±12.4 to 22.2±8.5) (P>0.05).

CONCLUSION

Red wavelength is safe and effective to be used to treat acne vulgaris by LLLT compared to infrared wavelength.

摘要

背景/目的:寻常痤疮是一种非常常见的皮肤疾病,在临床实践中仍然是一个主要问题。最近,已采用各种光谱的光疗法治疗痤疮。有证据表明,低强度激光疗法(LLLT)对痤疮皮损的治疗具有有益效果。在本研究中,评估了两种不同波长的LLLT(630和890nm)治疗寻常痤疮的效果。

材料和方法

本研究为单盲随机临床试验。纳入年龄在18岁以上的轻至中度寻常痤疮患者,分别在面部右侧和左侧接受红色LLLT(630nm)和红外LLLT(890nm)治疗,每周两次,共12次,并在基线以及第2、4、6和8周进行临床评估。

结果

28例患者参与了本研究。治疗10周后,630nm LLLT治疗侧的痤疮皮损显著减少(从27.7±12.7降至6.3±1.9)(P<0.001),但890nm LLLT治疗部位的减少不显著(从26.9±12.4降至22.2±8.5)(P>0.05)。

结论

与红外波长相比,红色波长的LLLT用于治疗寻常痤疮安全有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e893/3352636/cd5a3fdfcc48/IJD-57-128-g002.jpg

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