Schorling J B, McAuliffe J F, de Souza M A, Guerrant R L
Division of Geographic Medicine, University of Virginia School of Medicine, Charlottesville.
Int J Epidemiol. 1990 Sep;19(3):728-35. doi: 10.1093/ije/19.3.728.
This study was undertaken to further define the relationship between malnutrition and subsequent diarrhoeal illness among children. A cohort of 61 children under five years of age was followed for two years in an urban Brazilian slum. Nutritional status was determined at two-month intervals and was used to predict the subsequent occurrence of diarrhoea. A significant, graded association between worsened nutritional status, as measured by length- or weight-for-age, and diarrhoea incidence was found. This relationship was present for both two-month and one-year periods following nutritional assessment. The average duration of diarrhoea was also significantly longer during the two-month periods which were preceded by the worst nutritional status. Overall, the most malnourished children had nearly twice the total number of days of diarrhoea that better nourished children had. These results provide additional evidence that a significant association between malnutrition and both increased diarrhoea incidence and duration exists.
本研究旨在进一步明确儿童营养不良与随后发生的腹泻病之间的关系。在巴西城市贫民窟对61名五岁以下儿童进行了为期两年的队列研究。每隔两个月测定一次营养状况，并用于预测随后腹泻的发生情况。研究发现，以年龄别身长或体重衡量的营养状况恶化与腹泻发病率之间存在显著的分级关联。这种关系在营养评估后的两个月和一年期间均存在。在营养状况最差的两个月期间，腹泻的平均持续时间也显著更长。总体而言，营养不良最严重的儿童腹泻总天数几乎是营养状况较好儿童的两倍。这些结果提供了更多证据，证明营养不良与腹泻发病率增加和持续时间延长之间存在显著关联。
