Kirkwood J K, Wells G A, Wilesmith J W, Cunningham A A, Jackson S I
Veterinary Science Research Group, Institute of Zoology, London.
Vet Rec. 1990 Oct 27;127(17):418-20.
Clinical, pathological and epidemiological details of scrapie-like encephalopathies are described in an arabian oryx and a greater kudu. Clinical signs included ataxia and loss of condition with a short, progressive clinical course (22 and three days, respectively). Histopathological examination of the brains revealed spongiform encephalopathy characteristic of that observed in scrapie and bovine spongiform encephalopathy (BSE). It seems probable that these cases have a common aetiology with BSE. Scrapie-like spongiform encephalopathies have now been described in five species of exotic artiodactyls in Britain indicating a, hitherto inapparent, wider range of ruminant species as natural hosts for these diseases.
在一只阿拉伯大羚羊和一只大林羚身上描述了类羊瘙痒病脑病的临床、病理和流行病学细节。临床症状包括共济失调和身体状况下降,临床病程较短且呈进行性(分别为22天和3天)。对大脑的组织病理学检查显示出羊瘙痒病和牛海绵状脑病(BSE)中所观察到的海绵状脑病特征。这些病例似乎与BSE有共同的病因。目前在英国已在5种外来偶蹄动物中描述了类羊瘙痒病海绵状脑病,这表明这些疾病的天然宿主反刍动物种类范围比以往认为的更广,而此前这一范围并不明显。