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欧洲的癌症预防:地中海饮食作为一种保护选择。

Cancer prevention in Europe: the Mediterranean diet as a protective choice.

机构信息

Department of Surgery, University of Genoa, Genoa, Italy.

出版信息

Eur J Cancer Prev. 2013 Jan;22(1):90-5. doi: 10.1097/CEJ.0b013e328354d2d7.

Abstract

In the coming years, European death rates because of cancer will further decline, but the overall number of cases will increase, mostly as a consequence of the ageing of the population. The target for cancer prevention in Europe will remain a healthy diet and control of obesity in addition to a decrease in smoking. A healthy diet model in European countries is the traditional Mediterranean diet, which is based on abundant and variable plant foods, high consumption of cereals, olive oil as the main (added) fat, low intake of (red) meat and moderate consumption of wine. The Mediterranean diet is associated with a reduced risk of cardiovascular disease and cancer. The biological mechanisms for cancer prevention associated with the Mediterranean diet have been related to the favourable effect of a balanced ratio of omega 6 and omega 3 essential fatty acids and high amounts of fibre, antioxidants and polyphenols found in fruit, vegetables, olive oil and wine. The Mediterranean diet also involves a 'Mediterranean way of drinking', that is, regular, moderate consumption of wine mainly with food. This pattern of drinking increases longevity, reduces the risk of cardiovascular disease and does not appreciably influence the overall risk of cancer. However, heavy alcohol drinking is associated with digestive, upper respiratory tract, liver and breast cancers; therefore, avoidance or restriction of alcohol consumption to two drinks/day in men and one drink/day in women is a global public health priority.

摘要

在未来几年,欧洲因癌症导致的死亡率将进一步下降,但癌症总病例数将会增加,这主要是由于人口老龄化。欧洲癌症预防的目标仍然是健康饮食和控制肥胖,此外还要减少吸烟。欧洲国家的健康饮食模式是传统的地中海饮食,这种饮食以丰富多样的植物性食物为基础,大量食用谷物,以橄榄油作为主要(添加)脂肪,(红色)肉类摄入量低,适度饮酒。地中海饮食与降低心血管疾病和癌症的风险有关。与地中海饮食相关的癌症预防的生物学机制与平衡的ω-6 和 ω-3 必需脂肪酸比例以及水果、蔬菜、橄榄油和葡萄酒中大量纤维、抗氧化剂和多酚的有利影响有关。地中海饮食还涉及一种“地中海式的饮酒方式”,即定期、适度地饮用葡萄酒,主要与食物一起饮用。这种饮酒模式可以延长寿命,降低心血管疾病的风险,并且不会显著影响癌症的总体风险。然而,大量饮酒与消化系统、上呼吸道、肝脏和乳腺癌有关;因此,避免或限制男性每天饮酒两杯,女性每天饮酒一杯,是全球公共卫生的优先事项。

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