Department of Internal Medicine and Rehabilitation Science, Tohoku University, Graduate School of Medicine, Sendai, Japan.
J Am Geriatr Soc. 2012 Jun;60(6):1005-11. doi: 10.1111/j.1532-5415.2012.03977.x. Epub 2012 May 30.
To investigate the effects of lavender olfactory stimulation intervention on fall incidence in elderly nursing home residents.
Randomized placebo-controlled trial.
Three randomly selected nursing homes in northern Japan.
One hundred and forty-five nursing home residents aged 65 and older.
Participants were randomly assigned to the lavender (n = 73) or placebo group (n = 72) for a 360-day study period. The lavender group received continuous olfactory stimulation from a lavender patch. The placebo group received an unscented patch.
The primary outcome measure was resident falls. Other measurements taken at baseline and 12 months included functional ability (assessed using the Barthel Index), cognitive function (Mini-Mental State Examination (MMSE)), and behavioral and psychological problems associated with dementia (Cohen-Mansfield Agitation Inventory (CMAI)).
There were fewer fallers in the lavender group (n = 26) than in the placebo group (n = 36) (hazard ratio (HR)=0.57, 95% confidence interval (CI) = 0.34-0.95) and a lower incidence rate in the lavender group (1.04 per person-year) than in the placebo group (1.40 per person-year) (incidence rate ratio = 0.51, 95% CI = 0.30-0.88). The lavender group also had a significant decrease in CMAI score (P = .04) from baseline to follow-up in a per protocol analysis.
Lavender olfactory stimulation may reduce falls and agitation in elderly nursing home residents; further research is necessary to confirm these findings.
调查薰衣草嗅觉刺激干预对养老院老年居民跌倒发生率的影响。
随机安慰剂对照试验。
日本北部的三个随机选定的养老院。
145 名 65 岁及以上的养老院居民。
参与者被随机分配到薰衣草（n = 73）或安慰剂组（n = 72）进行 360 天的研究。薰衣草组接受薰衣草贴片的持续嗅觉刺激。安慰剂组接受无味贴片。
主要结局指标是居民跌倒。在基线和 12 个月时还进行了其他测量，包括功能能力（使用巴氏指数评估）、认知功能（简易精神状态检查（MMSE））以及与痴呆相关的行为和心理问题（科恩-曼斯菲尔德激惹量表（CMAI））。
薰衣草组跌倒者较少（n = 26），安慰剂组跌倒者较多（n = 36）（风险比（HR）= 0.57，95%置信区间（CI）= 0.34-0.95），且薰衣草组的发生率较低（1.04 人年），安慰剂组的发生率较高（1.40 人年）（发生率比= 0.51，95%CI = 0.30-0.88）。在按方案分析中，薰衣草组的 CMAI 评分也从基线到随访有显著下降（P =.04）。
薰衣草嗅觉刺激可能减少养老院老年居民的跌倒和激越；需要进一步研究来证实这些发现。
