Department of Systems Biology, Harvard Medical School, Boston, MA 02115, United States.
Curr Opin Chem Biol. 2012 Aug;16(3-4):337-44. doi: 10.1016/j.cbpa.2012.05.002. Epub 2012 May 29.
A recent resurgence in basic and applied research on photosynthesis has been driven in part by recognition that fulfilling future food and energy requirements will necessitate improvements in crop carbon-fixation efficiencies. Photosynthesis in traditional terrestrial crops is being reexamined in light of molecular strategies employed by photosynthetic microbes to enhance the activity of the Calvin cycle. Synthetic biology is well-situated to provide original approaches for compartmentalizing and enhancing photosynthetic reactions in a species independent manner. Furthermore, the elucidation of alternative carbon-fixation routes distinct from the Calvin cycle raises possibilities that novel pathways and organisms can be utilized to fix atmospheric carbon dioxide into useful materials.
最近,基础和应用光合作用研究的复兴部分是由于人们认识到,要满足未来的粮食和能源需求,就必须提高作物的碳固定效率。鉴于光合微生物用来提高卡尔文循环活性的分子策略,传统的陆地作物的光合作用正在重新被审视。合成生物学非常适合提供原始的方法,以独立于物种的方式分隔和增强光合作用反应。此外,阐明不同于卡尔文循环的替代碳固定途径,提出了利用新途径和生物体将大气二氧化碳固定为有用物质的可能性。