Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences.
Acta Naturae. 2011 Jan;3(1):29-47.
Semiconductor quantum dots (QDs) are a new class of fluorophores with unique physical and chemical properties, which allow to appreciably expand the possibilities for the current methods of fluorescent imaging and optical diagnostics. Here we discuss the prospects of QD application for molecular diagnostics of tumors ranging from cancer-specific marker detection on microplates to non-invasive tumor imagingin vivo. We also point out the essential problems that require resolution in order to clinically promote QD, and we indicate innovative approaches to oncology which are implementable using QD.
半导体量子点（QD）是一类具有独特物理和化学性质的新型荧光团，这使得当前的荧光成像和光学诊断方法的可能性得到了极大的扩展。在这里，我们讨论了 QD 在肿瘤的分子诊断中的应用前景，从微孔板上的癌症特异性标志物检测到体内的肿瘤无创成像。我们还指出了为了将 QD 推向临床应用需要解决的关键问题，并指出了使用 QD 实现的肿瘤学创新方法。
