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根治性前列腺切除术中保留膀胱颈的作用:临床与尿动力学研究

The role of bladder neck preservation during radical prostatectomy: clinical and urodynamic study.

作者信息

Grasso Marco, Torelli Fabrizio, Lania Caterina, Blanco Salvatore

机构信息

Department of Urology, San Gerardo, Hospital, Monza, Italy.

出版信息

Arch Ital Urol Androl. 2012 Mar;84(1):1-6.

Abstract

AIMS

Bladder neck preservation has caused an increase in urinary continence following radical prostatectomy, and has given rise to much controversy. We have reviewed our clinical and urodynamic experience collected since 1995 in patients subjected to radical prostatectomy with bladder neck preservation.

MATERIALS AND METHODS

180 patients were followed postoperatively using a pad test, an incontinence questionnaire and PSA dosage. In 66 early continent patients, test of maximum urethral closing pressure, functional length and active urethral continence were carried out, together with Valsalva leak point pressure tests and a pressure/flow study. The obtained data were then analysed.

RESULTS

Urinary continence was achieved in 132/180 men (73%) already two weeks after operation. Three months, six months and one year later the continence rate was 89%, 95.5% and 97.7% (176/180) respectively. As far as the urodynamic parameters of the 66 patients fully tested are concerned, all showed high results. The active urethral continence capacity exceeded 200 cm/water, and the Valsalva leak point pressure equalled or exceeded 150 cm/water.

CONCLUSIONS

Following an accurate dissection of the distal urethra, bladder neck preservation guarantees early recovery of continence, as confirmed by local urodynamic figures, and restores functional integration of both the urethral sphincteric-smooth proximal and distal striated units.

摘要

目的

保留膀胱颈可使根治性前列腺切除术后尿失禁发生率升高,引发诸多争议。我们回顾了自1995年以来对接受保留膀胱颈根治性前列腺切除术患者收集的临床及尿动力学经验。

材料与方法

对180例患者术后采用尿垫试验、尿失禁问卷及前列腺特异抗原(PSA)检测进行随访。对66例早期控尿患者进行最大尿道闭合压、功能长度及主动尿道控尿测试,同时进行瓦尔萨尔瓦漏点压测试及压力/流率研究。然后对所得数据进行分析。

结果

180例男性患者中,术后两周即有132例(73%)实现尿控。术后三个月、六个月及一年时,控尿率分别为89%、95.5%及97.7%(176/180)。就66例接受全面测试患者的尿动力学参数而言,所有结果均良好。主动尿道控尿能力超过200 cm水柱,瓦尔萨尔瓦漏点压等于或超过150 cm水柱。

结论

在对尿道远端进行精确解剖后,保留膀胱颈可确保早期恢复控尿,局部尿动力学数据证实了这一点,且恢复了尿道近端括约肌 - 平滑肌及远端横纹肌单位的功能整合。

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