Physician's Committee for Responsible Medicine, Department of Medicine, George Washington University, Washington, DC, USA.
J Trauma Dissociation. 2012;13(4):448-68. doi: 10.1080/15299732.2011.652346.
It is widely accepted that animals often experience pain and distress as a result of their use in scientific experimentation. However, unlike human suffering, the wide range of acute, recurrent, and chronic stressors and trauma on animals is rarely evaluated. In order to better understand the cumulative effects of captivity and laboratory research conditions on animals, we explore parallels between human experiences of pain and psychological distress and those of animals based on shared brain structures and physiological mechanisms. We review anatomical, physiological, and behavioral similarities between humans and other animals regarding the potential for suffering. In addition, we examine associations between research conditions and indicators of pain and distress. We include 4 case studies of common animal research protocols in order to illustrate incidental and experimental factors that can lead to animal suffering. Finally, we identify parallels between established traumatic conditions for humans and existing laboratory conditions for animals.
人们普遍认为，动物在科学实验中经常会因为被使用而感到痛苦和痛苦。然而，与人类的痛苦不同，动物所经历的急性、复发性和慢性应激源和创伤很少被评估。为了更好地理解圈养和实验室研究条件对动物的累积影响，我们根据共享的大脑结构和生理机制，探索了人类和动物在疼痛和心理困扰方面的相似之处。我们回顾了人类和其他动物在潜在痛苦方面的解剖学、生理学和行为学相似之处。此外，我们还研究了研究条件与疼痛和痛苦指标之间的关系。我们包括了 4 个常见的动物研究方案的案例研究，以说明可能导致动物痛苦的偶然和实验因素。最后，我们确定了人类既定的创伤条件与动物现有的实验室条件之间的相似之处。
