School of Nursing, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Sleep. 2012 Jun 1;35(6):727-34. doi: 10.5665/sleep.1846.
Chronic sleep deficiency, defined as a state of inadequate or mistimed sleep, is a growing and underappreciated determinant of health status. Sleep deprivation contributes to a number of molecular, immune, and neural changes that play a role in disease development, independent of primary sleep disorders. These changes in biological processes in response to chronic sleep deficiency may serve as etiological factors for the development and exacerbation of cardiovascular and metabolic diseases and, ultimately, a shortened lifespan. Sleep deprivation also results in significant impairments in cognitive and motor performance which increase the risk of motor vehicle crashes and work-related injuries and fatal accidents. The American Academy of Sleep Medicine and the Sleep Research Society have developed this statement to communicate to national health stakeholders the current knowledge which ties sufficient sleep and circadian alignment in adults to health.
慢性睡眠不足，定义为睡眠不足或睡眠时机不当的状态，是健康状况日益被忽视的重要决定因素。睡眠剥夺会导致许多分子、免疫和神经变化，这些变化在疾病发展中起作用，而与原发性睡眠障碍无关。这些针对慢性睡眠不足的生物过程变化可能是心血管和代谢疾病发展和恶化的病因因素，并最终导致寿命缩短。睡眠剥夺还会导致认知和运动表现显著受损，增加机动车事故和与工作相关的伤害和致命事故的风险。美国睡眠医学学会和睡眠研究学会制定了这份声明，旨在向国家卫生利益相关者传达目前的知识，即成年人充足的睡眠和昼夜节律协调与健康有关。
