Pine Keith, Sloan Brian, Stewart Joanna, Jacobs Robert J
Department of Optometry and Vision Science, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand.
Clin Ophthalmol. 2012;6:707-13. doi: 10.2147/OPTH.S31126. Epub 2012 May 10.
This study aimed to better understand the causes and treatments of mucoid discharge associated with prosthetic eye wear by reviewing the literature and surveying anophthalmic patients.
An anonymous questionnaire was completed by 429 prosthetic eye wearers who used visual analog scales to self-measure their discharge experience for four discharge characteristics: frequency, color, volume, and viscosity. These characteristics were analyzed with age, ethnicity, years wearing a prosthesis, eye loss cause, removal and cleaning regimes, hand-washing behavior, age of current prosthesis, and professional repolishing regimes as explanatory variables. Eighteen ocularists' Web sites containing comments on the cause and treatment of discharge were surveyed.
Associations were found between discharge frequency and cleaning regimes with more frequent cleaning accompanying more frequent discharge. Color was associated with years of wearing and age, with more years of wearing and older people having less colored discharge. Volume was associated with cleaning regimes with more frequent cleaners having more volume. Viscosity was associated with cleaning regimes and years of wearing with more frequent cleaning and shorter wearing time accompanying more viscous discharge. No associations were found between discharge characteristics and ethnicity, eye loss cause, hand washing, age of current prosthesis, or repolishing regimes. Forty-seven percent of ocularists' Web sites advised that discharge was caused by surface deposits on the prosthesis, 29% by excessive handling of the prosthesis, and 24% by other causes.
A standardized treatment protocol for managing discharge is lacking. More frequent prosthesis removal and cleaning was associated with more severe discharge, but the direction of cause and effect has not been established. Professional repolishing regimes had limited impact on discharge experience. Further research into the socket's response to prosthetic eye wear, including the physical, chemical, and biological elements of the conjunctiva, the socket fluids, and the deposits that cover the prosthetic eye is recommended.
本研究旨在通过回顾文献和调查无眼球患者,更好地了解与义眼佩戴相关的黏液性分泌物的成因及治疗方法。
429名义眼佩戴者完成了一份匿名问卷,他们使用视觉模拟量表对分泌物的四个特征进行自我测量:频率、颜色、量和黏稠度。以年龄、种族、佩戴义眼的年限、失明原因、摘除和清洁方式、洗手行为、当前义眼的使用年限以及专业修复方式作为解释变量,对这些特征进行分析。对18个包含分泌物成因及治疗相关评论的眼科专家网站进行了调查。
发现分泌物频率与清洁方式之间存在关联,清洁频率越高,分泌物越频繁。颜色与佩戴年限和年龄有关,佩戴年限越长、年龄越大,有色分泌物越少。量与清洁方式有关,清洁频率越高,量越大。黏稠度与清洁方式和佩戴年限有关,清洁频率越高、佩戴时间越短,分泌物越黏稠。在分泌物特征与种族、失明原因、洗手、当前义眼的使用年限或修复方式之间未发现关联。47%的眼科专家网站建议分泌物是由义眼表面沉积物引起的,29%是由义眼过度处理引起的,24%是由其他原因引起的。
缺乏针对分泌物管理的标准化治疗方案。义眼摘除和清洁频率越高,分泌物越严重,但因果关系尚未确立。专业修复方式对分泌物体验的影响有限。建议进一步研究眼窝对义眼佩戴的反应,包括结膜的物理、化学和生物学因素、眼窝液以及覆盖义眼的沉积物。