Biomicrofluidics. 2012 Jun;6(2):24110-241106. doi: 10.1063/1.4704520. Epub 2012 Apr 13.
We present a simple technique for creating an on-chip magnetic particle conveyor based on exchange-biased permalloy microstripes. The particle transportation relies on an array of stripes with a spacing smaller than their width in conjunction with a periodic sequence of four different externally applied magnetic fields. We demonstrate the controlled transportation of a large population of particles over several millimeters of distance as well as the spatial separation of two populations of magnetic particles with different magnetophoretic mobilities. The technique can be used for the controlled selective manipulation and separation of magnetically labelled species.
我们提出了一种基于交换偏置坡莫合金微带的片上磁性粒子输送的简单技术。该粒子输送依赖于具有小于其宽度的间距的条纹阵列以及四个不同外加磁场的周期性序列。我们展示了大量粒子在数毫米距离内的受控输送,以及具有不同磁泳动率的两种磁性粒子的空间分离。该技术可用于对磁性标记物种进行受控的选择性操作和分离。