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加拿大变应性鼻炎(AR)的负担:医生和患者的观点。

The burden of allergic rhinitis (AR) in Canada: perspectives of physicians and patients.

机构信息

McMaster University, Hamilton, ON, Canada.

出版信息

Allergy Asthma Clin Immunol. 2012 Jun 1;8(1):7. doi: 10.1186/1710-1492-8-7.

Abstract

BACKGROUND

Allergic rhinitis (AR) is a common problem and we sought to examine the burden of disease and its management in Canada from the perspectives of patients and physicians.

METHODS

Two parallel, Canadawide structured telephone interviews surveyed 1,001 AR patients and 160 physicians in July 2006.

RESULTS

44% of patients had experienced nasal symptoms unrelated to a cold and 20% had a physician diagnosis of AR. At screening 27% reported asthma, 15% chronic or recurrent sinusitis and 5% nasal polyps. With attacks nasal congestion and runny nose were the most bothersome symptoms. Other problems experienced were fatigue (46%), poor concentration (32%), and reduced productivity (23%). Most (77%) had not seen a physician in the past year. Physicians estimated they prescribed intranasal cortico steroids (INCS) to most AR patients (77%) consistent with guidelines but only 19% of patients had used one in the last month. Only 48% of patients were very satisfied with their current INCS. 41% of AR patients reported discontinuing their INCS with the most common reason being a perceived lack of long-lasting symptom relief (44%). 52% of patients felt that their current INCS lost effectiveness over 24 h. The most common INCS side effects included dripping down the throat, bad taste, and dryness. Most AR patients reported lifestyle limitations despite treatment (66%). 61% of patients felt that their symptoms were only somewhat controlled or poorly/not controlled during their worst month in the past year.

CONCLUSIONS

AR symptoms are common and many patients experience inadequate control. Physicians report they commonly prescribe intranasal corticosteroids, but patient's perceived loss of efficacy and side effects lead to their discontinuation. Persistent relief of allergic rhinitis symptoms remains a major unmet need. Better treatments and education are required.

摘要

背景

变应性鼻炎(AR)是一种常见的问题,我们试图从患者和医生的角度来考察加拿大的疾病负担及其管理。

方法

2006 年 7 月,我们进行了两次平行的、全加拿大范围的电话调查,调查了 1001 名 AR 患者和 160 名医生。

结果

44%的患者有过与感冒无关的鼻部症状,20%的患者被诊断为 AR。在筛查时,27%的患者报告有哮喘,15%的患者有慢性或复发性鼻窦炎,5%的患者有鼻息肉。发作时,鼻塞和流涕是最恼人的症状。其他问题还包括疲劳(46%)、注意力不集中(32%)和工作效率下降(23%)。大多数(77%)患者在过去一年中没有看过医生。医生估计,他们根据指南为大多数 AR 患者(77%)开了鼻腔皮质类固醇(INCS),但只有 19%的患者在过去一个月中使用过。只有 48%的患者对目前的 INCS 非常满意。41%的 AR 患者报告停止使用他们的 INCS,最常见的原因是他们认为没有持久的症状缓解(44%)。52%的患者认为他们目前的 INCS 在 24 小时内失去了效果。最常见的 INCS 副作用包括滴入喉咙、异味和干燥。尽管进行了治疗,但大多数 AR 患者(66%)报告生活方式受限。61%的患者认为他们在过去一年中症状最严重的一个月里,症状只是得到了一定程度的控制,或者控制得很差/没有得到控制。

结论

AR 症状很常见,许多患者的症状控制不理想。医生报告他们通常会开鼻腔皮质类固醇,但患者认为药物失去疗效和出现副作用会导致他们停药。持续缓解变应性鼻炎症状仍然是一个主要的未满足的需求。需要更好的治疗方法和教育。

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