Comprehensive Epilepsy Service, Royal Prince Alfred Hospital & The University of Sydney, Camperdown, Sydney, NSW 2050, Australia.
Seizure. 2012 Sep;21(7):491-5. doi: 10.1016/j.seizure.2012.04.015. Epub 2012 Jun 1.
ILAE guidelines recommend the use of prolonged EEG where the diagnosis of epilepsy or the classification of the seizure syndrome is proving difficult. Due to its limited provision, video EEG monitoring is unavailable to many patients under investigation(1). The aim of this study was to examine the utility of the alternate investigation of outpatient ambulatory EEG.
In this retrospective study we analysed 324 consecutive prolonged outpatient ambulatory EEGs lasting 72-96 h (4-5 days), without medication withdrawal. EEG data and the clinical record were reviewed to investigate the utility of the investigation.
Of 324 studies: 219 (68%) studies gave positive data, 116 (36%) showed interictal epileptiform discharges (IEDs), 167 (52%) had events. 105 (32%) studies were normal. Overall 51% of studies changed management of which 22% of studies changed the diagnosis and 29% of studies refined the diagnosis by classifying the epilepsy into focal or generalised.
The present study confirms the diagnostic utility of outpatient ambulatory EEG in the diagnosis of paroxysmal events.
ILAE 指南建议在癫痫的诊断或癫痫发作综合征的分类存在困难时使用长程 EEG。由于其供应有限,许多接受检查的患者无法进行视频 EEG 监测(1)。本研究旨在探讨门诊动态 EEG 替代检查的效用。
在这项回顾性研究中,我们分析了 324 例连续的、持续 72-96 小时(4-5 天)的门诊长程动态 EEG,没有药物撤药。回顾 EEG 数据和临床记录,以调查检查的效用。
在 324 项研究中:219 项(68%)研究提供了阳性数据,116 项(36%)显示出发作间期癫痫样放电(IEDs),167 项(52%)有事件。105 项(32%)研究正常。总的来说,51%的研究改变了治疗方法,其中 22%的研究改变了诊断,29%的研究通过将癫痫分类为局灶性或全面性来更精确地诊断。
本研究证实了门诊动态 EEG 在诊断阵发性事件中的诊断效用。